Publications [#233316] of Andrew T. McPhail

Journal Articles

  1. Wu, YC; Duh, CY; Chang, FR; Chang, GY; Wang, SK; Chang, JJ; McPhail, DR; McPhail, AT; Lee, KH, "The Crystal Structure and Cytotoxicity of Goniodiol Monoacetate from Goniothalamus Amyon", J. Nat. Prod., 1991, 54(4), 1077-1081 [Gateway.cgi], [doi].
    (last updated on 2026/01/21)

    Abstract:
    The styrylpyrone, goniodiol-7-monoacetate [1] [6R-(7R,8R-dihydro-7-acetoxy-8-hydroxystyryl)-5, 6-dihydro-2-pyrone], has been isolated from Goniothalamus amuyon, and its detailed molecular structure has been determined by X-ray crystallographic analysis. Goniodiol-7-monoacetate showed potent (ED50 values less than 0.1 microgram/ml) cytotoxicities against KB, P-388, RPMI, and TE671 tumor cells.