Publications [#233355] of Andrew T. McPhail

Journal Articles

  1. Wall, ME; Wani, MC; Manikumar, G; Taylor, H; Hughes, TJ; Gaetano, K; Gerwick, HW; McPhail, AT; McPhail, DR, "Plant antimutagenic agents, 7. Structure and antimutagenic properties of cymobarbatol and 4-isocymobarbatol, new cymopols from green alga (Cymopolia barbata).", Journal of natural productsSeptember,, 1989, 52(5), 1092-1099 [Gateway.cgi], [doi].
    (last updated on 2026/01/21)

    Abstract:
    Two new compounds, cymobarbatol and 4-isocymobarbatol, were isolated from the marine alga Cymopolia barbata. The complete structures and absolute stereochemistries of these compounds were elucidated by a variety of spectroscopic techniques and X-ray crystallography. Both compounds were found to be nontoxic over a broad concentration range to Salmonella typhimurium strains T-98 and T-100. Both compounds exhibited strong inhibition of the mutagenicity of 2-aminoanthracene and ethyl methanesulfonate toward, respectively, the T-98 strain plus a metabolic activator and T-100.