Publications [#233365] of Andrew T. McPhail

Journal Articles

  1. Yan, XZ; Kuo, YH; Lee, TJ; Shih, T; Chen, CH; McPhail, DR; McPhail, AT; Lee, KH, "Cytotoxic Components of Diospyros morrisiana", Phytochemistry, 1989, 28(5), 1541-1543, Elsevier BV [doi].
    (last updated on 2026/01/21)

    Abstract:
    Two cytotoxic compounds, isodiospyrin and β-amyrin, in addition to an inactive triterpene, olean-12-en-3-one, have been isolated from Diospyros morrisiana. The cytotoxic activity of isodiospyrin, which has ed50 values of 4.9 and 0.59 μg/ml, respectively, against HCT-8 colon tumour and P-388 lymphocytic leukemia, was demonstrated for the first time. Results of single-crystal X-ray analyses of β-amyrin acetate and olean-12-en-3-one are also reported. © 1989.