Publications [#233433] of Andrew T. McPhail

Journal Articles

  1. Mcphail, AT; Reginald Pinder, A, "Structure and synthesis of physoperuvine: x-ray crystal and molecular structures of the n-benzoyl derivatives of (±)-3- and (+)-4-methylaminocycloheptanone", TetrahedronJanuary,, 1984, 40(10), 1661-1666, Elsevier BV [Gateway.cgi], [doi].
    (last updated on 2026/01/21)

    Abstract:
    Single-crystal X-ray analyses have defined the structures and solid-state conformations of (±)-N-benzoyl-3-methylaminocycloheptanone [(±)-3]and (+)-N-benzoyl-4-methylaminocycloheptanone [(±)4]. Resolution of (±)-[4- methylaminocycloheptanone α 1-hydroxytropane]to yield the (+)-enantiomer. Identical in all respects with the free base from natural (+)-physoperuvine, was achieved via the di-p-toluoyl-(+)-tartrate salt. © 1984.