Publications [#233665] of Andrew T. McPhail

Journal Articles

  1. Aslanian, R; Lee, G; Iyer, RV; Shih, NY; Piwinski, JJ; Draper, RW; McPhail, AT, "An asymmetric synthesis of the novel H3 agonist (+)-(3R,4R)-3-(4-imidazolyl)-4-methylpyrrolidine dihydrochloride (Sch 50971)", Tetrahedron AsymmetryOctober,, 2000, 11(19), 3867-3871, Elsevier BV [Gateway.cgi], [doi].
    (last updated on 2026/01/21)

    Abstract:
    A short, high yielding, enantioselective synthesis of the novel H3 agonist Sch 50971 1 is described. The key enantiodifferentiating step is the 1,4-addition of a chiral N-propionyloxazolidinone to a nitroolefin. Copyright (C) 2000 Elsevier Science Ltd.