Publications [#233881] of Barbara R. Shaw

Journal Articles

  1. Li, P; Shaw, BR, "Synthesis of nucleoside 3',5'-cyclic boranophosphorothioate, a new type of cyclic nucleotide.", Chemical communications (Cambridge, England)December,, 2002(23), 2890-2891 [12478798], [doi].
    (last updated on 2024/04/24)

    Abstract:
    The first examples of a borane-containing doubly P-modified chiral cyclic nucleoside monophosphate (cNMP), e.g., thymidine and 5-fluoro-2'-deoxyuridine 3',5'-cyclic boranophosphorothioates, have been synthesized; these cNMP analogues with increased lipophilicity could be potential anticancer prodrugs and useful probes for mechanistic studies.