Publications [#233910] of Barbara R. Shaw

Journal Articles

  1. Wang, X; Dobrikov, M; Sergueev, D; Shaw, BR, "RNase H activation by stereoregular boranophosphate oligonucleotide.", Nucleosides, nucleotides & nucleic acidsMay,, 2003, 22(5-8), 1151-1153 [14565367], [doi].
    (last updated on 2024/03/28)

    Abstract:
    A stereoregular all-(Sp)-boranophosphate oligodeoxyribonucleotide (BH3(-)-ODN) 15-mer was synthesized using an enzymatic approach. The BH3(-)-ODN formed a hybrid with the complementary RNA 15-mer and induced RNase H hydrolysis of the RNA strand at ODN concentrations as low as 10 nM at 37 degrees C, but with a lower efficiency than that of its natural phosphodiester analogue.