Publications [#318053] of David N. Beratan
Journal Articles
- Polizzi, NF; Therien, MJ; Beratan, DN, "Mean First-Passage Times in Biology.", Israel journal of chemistryNovember,, 2016, 56(9-10), 816-824 [doi].
(last updated on 2024/09/26)Abstract:
Many biochemical processes, such as charge hopping or protein folding, can be described by an average timescale to reach a final state, starting from an initial state. Here, we provide a pedagogical treatment of the mean first-passage time (MFPT) of a physical process, which depends on the number of intervening states between the initial state and the target state. Our aim in this tutorial review is to provide a clear development of the mean first-passage time formalism and to show some of its practical utility. The MFPT treatment can provide a useful link between microscopic rates and the average timescales often probed by experiment.