Publications [#233160] of Dewey G. McCafferty

Journal Articles

  1. Barkallah, S; Schneider, SL; McCafferty, DG, "Facile syntheses of conformationally constrained analogues of lysine and homoglutamic acid", Tetrahedron LettersJuly,, 2005, 46(30), 4985-4987, Elsevier BV [doi].
    (last updated on 2024/07/16)

    Abstract:
    A facile divergent synthesis of the novel amino acid trans-4-aminoethyl-l- proline and trans-4-carboxymethyl-l-proline from commercially available trans-4-hydroxy-l-proline was developed. These conformationally constrained analogues of l-lysine and l-homoglutamic acid are useful proline templated amino acids (PTAAs) with potential applications in protein engineering and de novo protein design. © 2005 Elsevier Ltd. All rights reserved.