Publications of Emily R. Derbyshire

Preprints

  1. Keim, AI; Posfai, D; Haystead, TA; Derbyshire, ER, "Heat Shock Protein 90 is Critical for Plasmodium Parasite Liver Stage Development", FASEB JOURNALApril,, 2017, 31, 1 pages, FEDERATION AMER SOC EXP BIOL.

  2. Eubanks, AL; Derbyshire, ER, "Exploration of Plasmodium Kinases", FASEB JOURNALApril,, 2016, 30, 1 pages, FEDERATION AMER SOC EXP BIOL.

  3. Eubanks, AL; Derbyshire, ER, "Exploration of Plasmodium Kinases", FASEB JOURNALApril,, 2016, 30, 1 pages, FEDERATION AMER SOC EXP BIOL.

Journal Articles

  1. Mansfield, CR; Quan, B; Chirgwin, ME; Eduful, B; Hughes, PF; Neveu, G; Sylvester, K; Ryan, DH; Kafsack, BFC; Haystead, TAJ; Leahy, JW; Fitzgerald, MC; Derbyshire, ER, "Selective targeting of Plasmodium falciparum Hsp90 disrupts the 26S proteasome.", Cell Chem BiolApril,, 2024, 31(4), 729-742.e13 [doi] [abs].

  2. Mansfield, CR; Derbyshire, ER, "Meet the Authors: Christopher R. Mansfield and Emily R. Derbyshire.", Cell chemical biologyApril,, 2024, 31(4), 625-626 [doi] [abs].

  3. Schroeder, EA; Toro-Moreno, M; Raphemot, R; Sylvester, K; Colón, IC; Derbyshire, ER, "Toxoplasma and Plasmodium associate with host Arfs during infection.", edited by Blader, IJ , mSphereMarch,, 2024, 9(3), e0077023, American Society for Microbiology [doi] [abs].

  4. Ong, HW; de Silva, C; Avalani, K; Kwarcinski, F; Mansfield, CR; Chirgwin, M; Truong, A; Derbyshire, ER; Zutshi, R; Drewry, DH, "Characterization of 2,4-Dianilinopyrimidines Against Five P. falciparum Kinases PfARK1, PfARK3, PfNEK3, PfPK9, and PfPKB.", ACS medicinal chemistry lettersDecember,, 2023, 14(12), 1774-1784 [doi] [abs].

  5. D'Ambrosio, HK; Keeler, AM; Derbyshire, ER, "Examination of Secondary Metabolite Biosynthesis in Apicomplexa.", Chembiochem : a European journal of chemical biologySeptember,, 2023, 24(17), e202300263 [doi] [abs].

  6. Keeler, AM; Petruzziello, PE; Boger, EG; D'Ambrosio, HK; Derbyshire, ER, "Exploring the Chain Release Mechanism from an Atypical Apicomplexan Polyketide Synthase.", BiochemistrySeptember,, 2023, 62(17), 2677-2688 [doi] [abs].

  7. Mansfield, CR; Chirgwin, ME; Derbyshire, ER, "Labeling strategies to track protozoan parasite proteome dynamics.", Current opinion in chemical biologyAugust,, 2023, 75, 102316 [doi] [abs].

  8. Viswanathan, NK; Chirgwin, ME; Gibbs, J; Kalaj, BN; Durham, S; Tran, J; Gomez, M; Lazaro, H; Chen, M; Mansfield, CR; Derbyshire, ER; Eagon, S, "Synthesis and activity of β-carboline antimalarials targeting the Plasmodium falciparum heat shock 90 protein.", Bioorganic & medicinal chemistry lettersAugust,, 2023, 92, 129410 [doi] [abs].

  9. Keeler, AM; D'Ambrosio, HK; Ganley, JG; Derbyshire, ER, "Characterization of Unexpected Self-Acylation Activity of Acyl Carrier Proteins in a Modular Type I Apicomplexan Polyketide Synthase.", ACS chemical biologyApril,, 2023, 18(4), 785-793 [doi] [abs].

  10. Ong, HW; Truong, A; Kwarcinski, F; de Silva, C; Avalani, K; Havener, TM; Chirgwin, M; Galal, KA; Willis, C; Krämer, A; Liu, S; Knapp, S; Derbyshire, ER; Zutshi, R; Drewry, DH, "Discovery of potent Plasmodium falciparum protein kinase 6 (PfPK6) inhibitors with a type II inhibitor pharmacophore.", European journal of medicinal chemistryMarch,, 2023, 249, 115043 [doi] [abs].

  11. Galal, KA; Truong, A; Kwarcinski, F; de Silva, C; Avalani, K; Havener, TM; Chirgwin, ME; Merten, E; Ong, HW; Willis, C; Abdelwaly, A; Helal, MA; Derbyshire, ER; Zutshi, R; Drewry, DH, "Identification of Novel 2,4,5-Trisubstituted Pyrimidines as Potent Dual Inhibitors of Plasmodial PfGSK3/PfPK6 with Activity against Blood Stage Parasites In Vitro.", Journal of medicinal chemistryOctober,, 2022, 65(19), 13172-13197 [doi] [abs].

  12. Chirgwin, ME; Schroeder, EA; Derbyshire, ER, "Cut it out! A CRISPR-Cas9 screen identifies host regulators of the Plasmodium liver stage.", Cell chemical biologySeptember,, 2022, 29(9), 1365-1367 [doi] [abs].

  13. Mughal, H; Bell, EC; Mughal, K; Derbyshire, ER; Freundlich, JS, "Random Forest Model Predictions Afford Dual-Stage Antimalarial Agents.", ACS infectious diseasesAugust,, 2022, 8(8), 1553-1562 [doi] [abs].

  14. Tye, MA; Payne, NC; Johansson, C; Singh, K; Santos, SA; Fagbami, L; Pant, A; Sylvester, K; Luth, MR; Marques, S; Whitman, M; Mota, MM; Winzeler, EA; Lukens, AK; Derbyshire, ER; Oppermann, U; Wirth, DF; Mazitschek, R, "Elucidating the path to Plasmodium prolyl-tRNA synthetase inhibitors that overcome halofuginone resistance.", Nature communicationsAugust,, 2022, 13(1), 4976 [doi] [abs].

  15. D'Ambrosio, HK; Ganley, JG; Keeler, AM; Derbyshire, ER, "Erratum: A single amino acid residue controls acyltransferase activity in a polyketide synthase from Toxoplasma gondii.", iScienceJuly,, 2022, 25(7), 104608 [doi] [abs].

  16. Schroeder, EA; Chirgwin, ME; Derbyshire, ER, "Plasmodium's fight for survival: escaping elimination while acquiring nutrients.", Trends in parasitologyJuly,, 2022, 38(7), 544-557 [doi] [abs].

  17. D'Ambrosio, HK; Ganley, JG; Keeler, AM; Derbyshire, ER, "A single amino acid residue controls acyltransferase activity in a polyketide synthase from Toxoplasma gondii.", iScienceJune,, 2022, 25(6), 104443 [doi] [abs].

  18. Lu, K-Y; Mansfield, CR; Fitzgerald, MC; Derbyshire, ER, "Chemoproteomics for Plasmodium Parasite Drug Target Discovery.", Chembiochem : a European journal of chemical biologyAugust,, 2021, 22(16), 2591-2599 [doi] [abs].

  19. Bang, S; Donnelly, CR; Luo, X; Toro-Moreno, M; Tao, X; Wang, Z; Chandra, S; Bortsov, AV; Derbyshire, ER; Ji, R-R, "Activation of GPR37 in macrophages confers protection against infection-induced sepsis and pain-like behaviour in mice.", Nat CommunMarch,, 2021, 12(1), 1704 [doi] [abs].

  20. Sylvester, K; Maher, SP; Posfai, D; Tran, MK; Crawford, MC; Vantaux, A; Witkowski, B; Kyle, DE; Derbyshire, ER, "Characterization of the Tubovesicular Network in Plasmodium vivax Liver Stage Hypnozoites and Schizonts.", Frontiers in cellular and infection microbiologyJanuary,, 2021, 11, 687019 [doi] [abs].

  21. Lu, K-Y; Pasaje, CFA; Srivastava, T; Loiselle, DR; Niles, JC; Derbyshire, E, "Phosphatidylinositol 3-phosphate and Hsp70 protect Plasmodium falciparum from heat-induced cell death.", eLifeSeptember,, 2020, 9, e56773 [doi] [abs].

  22. Ganley, JG; Pandey, A; Sylvester, K; Lu, K-Y; Toro-Moreno, M; Rütschlin, S; Bradford, JM; Champion, CJ; Böttcher, T; Xu, J; Derbyshire, ER, "A Systematic Analysis of Mosquito-Microbiome Biosynthetic Gene Clusters Reveals Antimalarial Siderophores that Reduce Mosquito Reproduction Capacity.", Cell chemical biologyJuly,, 2020, 27(7), 817-826.e5 [doi] [abs].

  23. Posfai, D; Maher, SP; Roesch, C; Vantaux, A; Sylvester, K; Péneau, J; Popovici, J; Kyle, DE; Witkowski, B; Derbyshire, ER, "Plasmodium vivax Liver and Blood Stages Recruit the Druggable Host Membrane Channel Aquaporin-3.", Cell chemical biologyJune,, 2020, 27(6), 719-727.e5 [doi] [abs].

  24. Ganley, JG; D'Ambrosio, HK; Shieh, M; Derbyshire, ER, "Coculturing of Mosquito-Microbiome Bacteria Promotes Heme Degradation in Elizabethkingia anophelis.", Chembiochem : a European journal of chemical biologyMay,, 2020, 21(9), 1279-1284 [doi] [abs].

  25. Lu, K-Y; Quan, B; Sylvester, K; Srivastava, T; Fitzgerald, MC; Derbyshire, ER, "Plasmodium chaperonin TRiC/CCT identified as a target of the antihistamine clemastine using parallel chemoproteomic strategy.", Proceedings of the National Academy of Sciences of the United States of AmericaMarch,, 2020, 117(11), 5810-5817 [doi] [abs].

  26. Lu, K-Y; Derbyshire, ER, "Tafenoquine: A Step toward Malaria Elimination.", BiochemistryMarch,, 2020, 59(8), 911-920 [doi] [abs].

  27. Toro-Moreno, M; Derbyshire, ER, "It's about Time: Insights into the Modes of Action of Antimalarials.", Cell chemical biologyFebruary,, 2020, 27(2), 139-141 [doi] [abs].

  28. Toro-Moreno, M; Sylvester, K; Srivastava, T; Posfai, D; Derbyshire, ER, "RNA-Seq Analysis Illuminates the Early Stages of Plasmodium Liver Infection.", mBioFebruary,, 2020, 11(1), e03234-e03219 [doi] [abs].

  29. D'Ambrosio, HK; Derbyshire, ER, "Investigating the Role of Class I Adenylate-Forming Enzymes in Natural Product Biosynthesis.", ACS chemical biologyJanuary,, 2020, 15(1), 17-27 [doi] [abs].

  30. Ganley, JG; Derbyshire, ER, "Linking Genes to Molecules in Eukaryotic Sources: An Endeavor to Expand Our Biosynthetic Repertoire.", Molecules (Basel, Switzerland)January,, 2020, 25(3), E625 [doi] [abs].

  31. Raphemot, R; Toro-Moreno, M; Lu, K-Y; Posfai, D; Derbyshire, ER, "Discovery of Druggable Host Factors Critical to Plasmodium Liver-Stage Infection.", Cell chemical biologySeptember,, 2019, 26(9), 1253-1262.e5 [doi] [abs].

  32. Szamosvári, D; Sylvester, K; Schmid, P; Lu, K-Y; Derbyshire, ER; Böttcher, T, "Close the ring to break the cycle: tandem quinolone-alkyne-cyclisation gives access to tricyclic pyrrolo[1,2-a]quinolin-5-ones with potent anti-protozoal activity.", Chemical communications (Cambridge, England)June,, 2019, 55(49), 7009-7012 [doi] [abs].

  33. Lee, H; Sylvester, K; Derbyshire, ER; Hong, J, "Synthesis and Analysis of Natural-Product-Like Macrocycles by Tandem Oxidation/Oxa-Conjugate Addition Reactions.", Chemistry (Weinheim an der Bergstrasse, Germany)May,, 2019, 25(26), 6500-6504 [doi] [abs].

  34. Raphemot, R; Eubanks, AL; Toro-Moreno, M; Geiger, RA; Hughes, PF; Lu, K-Y; Haystead, TAJ; Derbyshire, ER, "Plasmodium PK9 Inhibitors Promote Growth of Liver-Stage Parasites.", Cell Chem BiolMarch,, 2019, 26(3), 411-419.e7 [doi] [abs].

  35. Eubanks, AL; Perkins, MM; Sylvester, K; Ganley, JG; Posfai, D; Sanschargrin, PC; Hong, J; Sliz, P; Derbyshire, ER, "In silico Screening and Evaluation of Plasmodium falciparum Protein Kinase 5 (PK5) Inhibitors.", ChemMedChemDecember,, 2018, 13(23), 2479-2483 [doi] [abs].

  36. Ganley, JG; Carr, G; Ioerger, TR; Sacchettini, JC; Clardy, J; Derbyshire, ER, "Discovery of Antimicrobial Lipodepsipeptides Produced by a Serratia sp. within Mosquito Microbiomes.", Chembiochem : a European journal of chemical biologyAugust,, 2018, 19(15), 1590-1594 [doi] [abs].

  37. Posfai, D; Sylvester, K; Reddy, A; Ganley, JG; Wirth, J; Cullen, QE; Dave, T; Kato, N; Dave, SS; Derbyshire, ER, "Plasmodium parasite exploits host aquaporin-3 during liver stage malaria infection", PLOS PATHOGENSMay,, 2018, 14(5), 26 pages, PUBLIC LIBRARY SCIENCE [doi].

  38. Posfai, D; Sylvester, K; Reddy, A; Ganley, JG; Wirth, J; Cullen, QE; Dave, T; Kato, N; Dave, SS; Derbyshire, ER, "Plasmodium parasite exploits host aquaporin-3 during liver stage malaria infection.", PLoS PathogMay,, 2018, 14(5), e1007057 [doi] [abs].

  39. Posfai, D; Eubanks, AL; Keim, AI; Lu, K-Y; Wang, GZ; Hughes, PF; Kato, N; Haystead, TA; Derbyshire, ER, "Identification of Hsp90 Inhibitors with Anti-Plasmodium Activity.", Antimicrob Agents ChemotherApril,, 2018, 62(4) [doi] [abs].

  40. Ganley, JG; Toro-Moreno, M; Derbyshire, ER, "Exploring the Untapped Biosynthetic Potential of Apicomplexan Parasites.", BiochemistryJanuary,, 2018, 57(4), 365-375 [doi] [abs].

  41. Totzke, J; Gurbani, D; Raphemot, R; Hughes, PF; Bodoor, K; Carlson, DA; Loiselle, DR; Bera, AK; Eibschutz, LS; Perkins, MM; Eubanks, AL; Campbell, PL; Fox, DA; Westover, KD; Haystead, TAJ; Derbyshire, ER, "Takinib, a Selective TAK1 Inhibitor, Broadens the Therapeutic Efficacy of TNF-α Inhibition for Cancer and Autoimmune Disease.", Cell Chem BiolAugust,, 2017, 24(8), 1029-1039.e7 [doi] [abs].

  42. Kato, N; Comer, E; Sakata-Kato, T; Sharma, A; Sharma, M; Maetani, M; Bastien, J; Brancucci, NM; Bittker, JA; Corey, V; Clarke, D; Derbyshire, ER; Dornan, GL; Duffy, S; Eckley, S; Itoe, MA; Koolen, KMJ; Lewis, TA; Lui, PS; Lukens, AK; Lund, E; March, S; Meibalan, E; Meier, BC; McPhail, JA; Mitasev, B; Moss, EL; Sayes, M; Van Gessel, Y; Wawer, MJ; Yoshinaga, T; Zeeman, A-M; Avery, VM; Bhatia, SN; Burke, JE; Catteruccia, F; Clardy, JC; Clemons, PA; Dechering, KJ; Duvall, JR; Foley, MA; Gusovsky, F; Kocken, CHM; Marti, M; Morningstar, ML; Munoz, B; Neafsey, DE; Sharma, A; Winzeler, EA; Wirth, DF; Scherer, CA; Schreiber, SL, "Diversity-oriented synthesis yields novel multistage antimalarial inhibitors.", NatureOctober,, 2016, 538(7625), 344-349 [doi] [abs].

  43. Raphemot, R; Posfai, D; Derbyshire, ER, "Current therapies and future possibilities for drug development against liver-stage malaria.", The Journal of clinical investigationJune,, 2016, 126(6), 2013-2020 [doi] [abs].

  44. Raphemot, R; Lafuente-Monasterio, MJ; Gamo-Benito, FJ; Clardy, J; Derbyshire, ER, "Discovery of Dual-Stage Malaria Inhibitors with New Targets.", Antimicrobial agents and chemotherapyDecember,, 2015, 60(3), 1430-1437 [doi] [abs].

  45. Herman, JD; Pepper, LR; Cortese, JF; Estiu, G; Galinsky, K; Zuzarte-Luis, V; Derbyshire, ER; Ribacke, U; Lukens, AK; Santos, SA; Patel, V; Clish, CB; Sullivan, WJ; Zhou, H; Bopp, SE; Schimmel, P; Lindquist, S; Clardy, J; Mota, MM; Keller, TL; Whitman, M; Wiest, O; Wirth, DF; Mazitschek, R, "The cytoplasmic prolyl-tRNA synthetase of the malaria parasite is a dual-stage target of febrifugine and its analogs.", Science translational medicineMay,, 2015, 7(288), 288ra77 [doi] [abs].

  46. Derbyshire, ER; Zuzarte-Luís, V; Magalhães, AD; Kato, N; Sanschagrin, PC; Wang, J; Zhou, W; Miduturu, CV; Mazitschek, R; Sliz, P; Mota, MM; Gray, NS; Clardy, J, "Chemical interrogation of the malaria kinome.", Chembiochem : a European journal of chemical biologySeptember,, 2014, 15(13), 1920-1930 [doi] [abs].

  47. Derbyshire, ER; Min, J; Guiguemde, WA; Clark, JA; Connelly, MC; Magalhães, AD; Guy, RK; Clardy, J, "Dihydroquinazolinone inhibitors of proliferation of blood and liver stage malaria parasites.", Antimicrobial agents and chemotherapyJanuary,, 2014, 58(3), 1516-1522 [24366746], [doi] [abs].

  48. Derbyshire, ER; Clardy, J, "Closing in on a new treatment for sleeping sickness.", eLifeJuly,, 2013, 2, e01042 [23853715], [doi] [abs].

  49. Fernhoff, NB; Derbyshire, ER; Underbakke, ES; Marletta, MA, "Heme-assisted S-nitrosation desensitizes ferric soluble guanylate cyclase to nitric oxide.", The Journal of biological chemistryDecember,, 2012, 287(51), 43053-43062 [23093402], [doi] [abs].

  50. Gunn, A; Derbyshire, ER; Marletta, MA; Britt, RD, "Conformationally distinct five-coordinate heme-NO complexes of soluble guanylate cyclase elucidated by multifrequency electron paramagnetic resonance (EPR).", BiochemistryOctober,, 2012, 51(42), 8384-8390 [22985445], [doi] [abs].

  51. Carr, G; Derbyshire, ER; Caldera, E; Currie, CR; Clardy, J, "Antibiotic and antimalarial quinones from fungus-growing ant-associated Pseudonocardia sp.", Journal of natural productsOctober,, 2012, 75(10), 1806-1809 [23025282], [doi] [abs].

  52. Derbyshire, ER; Mazitschek, R; Clardy, J, "Characterization of Plasmodium liver stage inhibition by halofuginone.", ChemMedChemMay,, 2012, 7(5), 844-849 [22438279], [doi] [abs].

  53. Derbyshire, ER; Prudêncio, M; Mota, MM; Clardy, J, "Liver-stage malaria parasites vulnerable to diverse chemical scaffolds.", Proceedings of the National Academy of Sciences of the United States of AmericaMay,, 2012, 109(22), 8511-8516 [22586124], [doi] [abs].

  54. Derbyshire, ER; Marletta, MA, "Structure and regulation of soluble guanylate cyclase.", Annual review of biochemistryJanuary,, 2012, 81, 533-559 [22404633], [doi] [abs].

  55. Dong, CK; Urgaonkar, S; Cortese, JF; Gamo, F-J; Garcia-Bustos, JF; Lafuente, MJ; Patel, V; Ross, L; Coleman, BI; Derbyshire, ER; Clish, CB; Serrano, AE; Cromwell, M; Barker, RH; Dvorin, JD; Duraisingh, MT; Wirth, DF; Clardy, J; Mazitschek, R, "Identification and validation of tetracyclic benzothiazepines as Plasmodium falciparum cytochrome bc1 inhibitors.", Chemistry & biologyDecember,, 2011, 18(12), 1602-1610 [22195562], [doi] [abs].

  56. Derbyshire, ER; Mota, MM; Clardy, J, "The next opportunity in anti-malaria drug discovery: the liver stage.", PLoS pathogensSeptember,, 2011, 7(9), e1002178 [21966266], [doi].

  57. Derbyshire, ER; Winter, MB; Ibrahim, M; Deng, S; Spiro, TG; Marletta, MA, "Probing domain interactions in soluble guanylate cyclase.", BiochemistryMay,, 2011, 50(20), 4281-4290 [21491957], [doi] [abs].

  58. Derbyshire, ER; Deng, S; Marletta, MA, "Incorporation of tyrosine and glutamine residues into the soluble guanylate cyclase heme distal pocket alters NO and O2 binding.", The Journal of biological chemistryJune,, 2010, 285(23), 17471-17478 [20231286], [doi] [abs].

  59. Ibrahim, M; Derbyshire, ER; Soldatova, AV; Marletta, MA; Spiro, TG, "Soluble guanylate cyclase is activated differently by excess NO and by YC-1: resonance Raman spectroscopic evidence.", BiochemistryJune,, 2010, 49(23), 4864-4871 [20459051], [doi] [abs].

  60. Ibrahim, M; Derbyshire, ER; Marletta, MA; Spiro, TG, "Probing soluble guanylate cyclase activation by CO and YC-1 using resonance Raman spectroscopy.", BiochemistryMay,, 2010, 49(18), 3815-3823 [20353168], [doi] [abs].

  61. Fernhoff, NB; Derbyshire, ER; Marletta, MA, "A nitric oxide/cysteine interaction mediates the activation of soluble guanylate cyclase.", Proceedings of the National Academy of Sciences of the United States of AmericaDecember,, 2009, 106(51), 21602-21607 [20007374], [doi] [abs].

  62. Derbyshire, ER; Fernhoff, NB; Deng, S; Marletta, MA, "Nucleotide regulation of soluble guanylate cyclase substrate specificity.", BiochemistryAugust,, 2009, 48(31), 7519-7524 [19527054], [doi] [abs].

  63. Ibrahim, M; Derbyshire, ER; Marletta, MA; Spiro, TG, "Interaction of allosteric effectors with soluble guanylate cyclase heme domains: Role of heme distortion and propionate hydrogen bonding on synergistic activation", ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETYMarch,, 2009, 237, 1 pages, AMER CHEMICAL SOC [Gateway.cgi].

  64. Derbyshire, ER; Marletta, MA, "Biochemistry of soluble guanylate cyclase.", Handbook of experimental pharmacologyJanuary,, 2009(191), 17-31 [19089323], [doi] [abs].

  65. Winger, JA; Derbyshire, ER; Lamers, MH; Marletta, MA; Kuriyan, J, "The crystal structure of the catalytic domain of a eukaryotic guanylate cyclase.", BMC structural biologyOctober,, 2008, 8, 42 [18842118], [doi] [abs].

  66. Derbyshire, ER; Gunn, A; Ibrahim, M; Spiro, TG; Britt, RD; Marletta, MA, "Characterization of two different five-coordinate soluble guanylate cyclase ferrous-nitrosyl complexes.", BiochemistryMarch,, 2008, 47(12), 3892-3899 [18302323], [doi] [abs].

  67. Derbyshire, ER; Marletta, MA, "Butyl isocyanide as a probe of the activation mechanism of soluble guanylate cyclase. Investigating the role of non-heme nitric oxide.", The Journal of biological chemistryDecember,, 2007, 282(49), 35741-35748 [17916555], [doi] [abs].

  68. Martin, NI; Derbyshire, ER; Marletta, MA, "Synthesis and evaluation of a phosphonate analogue of the soluble guanylate cyclase activator YC-1.", Bioorganic & medicinal chemistry lettersSeptember,, 2007, 17(17), 4938-4941 [17587571], [doi] [abs].

  69. Winger, JA; Derbyshire, ER; Marletta, MA, "Dissociation of nitric oxide from soluble guanylate cyclase and heme-nitric oxide/oxygen binding domain constructs.", The Journal of biological chemistryJanuary,, 2007, 282(2), 897-907 [17098738], [doi] [abs].

  70. Cary, SPL; Winger, JA; Derbyshire, ER; Marletta, MA, "Nitric oxide signaling: no longer simply on or off.", Trends in biochemical sciencesApril,, 2006, 31(4), 231-239 [16530415], [doi] [abs].

  71. Derbyshire, ER; Tran, R; Mathies, RA; Marletta, MA, "Characterization of nitrosoalkane binding and activation of soluble guanylate cyclase.", BiochemistryDecember,, 2005, 44(49), 16257-16265 [16331986], [doi] [abs].