Publications [#330250] of Michael J. Therien

Papers Published

  1. Thérien, M; Fitzsimmons, BJ; Scheigets, J; Macdonald, D; Choo, LY; Guay, J; Falgueyret, JP; Riendeau, D, "Justicidin E: A new leukotriene biosynthesis inhibitor.", Bioorganic and Medicinal Chemistry LettersJanuary,, 1993, 3(10), 2063-2066, Elsevier BV [doi].
    (last updated on 2026/01/19)

    Abstract:
    Justicidin E, an arylnaphthalene lignan, has been identified as a potent inhibitor of leukotriene biosynthesis by human leukocytes (IC50 = 70 nM) and a non-redox inhibitor of 5-lipoxygenase activity. © 1993.