Publications [#234256] of Qiu Wang

Journal Articles

  1. McDonald, SL; Wang, Q, "α-Amination of Phosphonates: A Direct Synthesis of α-Amino Phosphonic Acids and Their Derivatives", SynlettJuly,, 2014, 25(16), 2233-2238, Georg Thieme Verlag KG [doi].
    (last updated on 2024/11/19)

    Abstract:
    A direct approach to access important α-amino phosphonic acids and their derivatives through the formation of C-N bonds is described. Several α-amination reactions of phosphonates that involve electrophilic aminating agents are reviewed. A recent development is highlighted in which an acyclic or cyclic amine is introduced into the α-position of a phosphonate in one step through deprotonative formation of an α-zincate followed by copper-catalyzed amination with an O-acylhydroxylamine. © Georg Thieme Verlag.