Publications [#323193] of Qiu Wang
Journal Articles
- Hemric, BN; Wang, Q, "Copper-catalyzed intermolecular oxyamination of olefins using carboxylic acids and O-benzoylhydroxylamines.", Beilstein journal of organic chemistryJanuary,, 2016, 12, 22-28 [doi].
(last updated on 2024/11/19)Abstract:
This paper reports a novel approach for the direct and facile synthesis of 1,2-oxyamino moieties via an intermolecular copper-catalyzed oxyamination of olefins. This strategy utilizes O-benzoylhydroxylamines as an electrophilic amine source and carboxylic acids as a nucleophilic oxygen source to achieve a modular difunctionalization of olefins. The reaction proceeded in a regioselective manner with moderate to good yields, exhibiting a broad scope of carboxylic acid, amine, and olefin substrates.