Publications [#152110] of Lesley H Curtis

Papers Published

1. AF Hernandez, AM Shea, CA Milano, JG Rogers, BG Hammill, CM O'Connor, KA Schulman, ED Peterson, LH Curtis, Long-term outcomes and costs of ventricular assist devices among Medicare beneficiaries., JAMA : the journal of the American Medical Association, vol. 300 no. 20 (November, 2008), pp. 2398-406, ISSN 1538-3598 [doi]
   (last updated on 2013/07/01)

   Abstract:
   BACKGROUND: In 2003, Medicare expanded coverage of ventricular assist devices as destination, or permanent, therapy for end-stage heart failure. Little is known about the long-term outcomes and costs associated with these devices. OBJECTIVE: To examine the acute and long-term outcomes of Medicare beneficiaries receiving ventricular assist devices alone or after open-heart surgery. METHODS: Analysis of inpatient claims from the Centers for Medicare & Medicaid Services for the period 2000 through 2006. Patients were Medicare fee-for-service beneficiaries who received a ventricular assist device between February 2000 and June 2006 alone as primary therapy (primary device group; n = 1476) or after cardiotomy in the previous 30 days (postcardiotomy group; n = 1467). METHODS: Cumulative incidence of device replacement, device removal, heart transplantation, readmission, and death, accounting for censoring and competing risks. Patients were followed up for at least 6 months and factors independently associated with long-term survival were identified. Medicare payments were used to calculate total inpatient costs and costs per day outside the hospital. RESULTS: Overall 1-year survival was 51.6% (n = 669) in the primary device group and 30.8% (n = 424) in the postcardiotomy group. Among primary device patients, 815 (55.2%) were discharged alive with a device. Of those, 450 (55.6%) were readmitted within 6 months and 504 (73.2%) were alive at 1 year. Of the 493 (33.6%) postcardiotomy patients discharged alive with a device, 237 (48.3%) were readmitted within 6 months and 355 (76.6%) were alive at 1 year. Mean 1-year Medicare payments for inpatient care for patients in the 2000-2005 cohorts were $178,714 (SD, $142,549) in the primary device group and $111,769 (SD, $95,413) in the postcardiotomy group. CONCLUSIONS: Among Medicare beneficiaries receiving a ventricular assist device, early mortality, morbidity, and costs remain high. Improving patient selection and reducing perioperative mortality are critical for improving overall outcomes.

   Keywords:
   Aged • Cardiac Surgical Procedures • Equipment Failure • Female • Health Care Costs* • Heart Failure • Heart-Assist Devices* • Hospitalization • Humans • Male • Medicare • Middle Aged • Morbidity • Patient Readmission • Retrospective Studies • Risk • Survival Analysis • Treatment Outcome • United States • economics • economics* • mortality • therapy*