Publications [#280131] of David J. Brady
- Greenberg, JA; Lakshmanan, MN; Brady, DJ; Kapadia, AJ, Optimization of a coded aperture coherent scatter spectral imaging system for medical imaging,
Progress in Biomedical Optics and Imaging Proceedings of Spie, vol. 9412
(January, 2015), SPIE, ISSN 1605-7422, ISBN 9781628415025 [doi]
(last updated on 2019/11/11)
© 2015 SPIE. Coherent scatter X-ray imaging is a technique that provides spatially-resolved information about the molecular structure of the material under investigation, yielding material-specific contrast that can aid medical diagnosis and inform treatment. In this study, we demonstrate a coherent-scatter imaging approach based on the use of coded apertures (known as coded aperture coherent scatter spectral imaging1, 2) that enables fast, dose-efficient, high-resolution scatter imaging of biologically-relevant materials. Specifically, we discuss how to optimize a coded aperture coherent scatter imaging system for a particular set of objects and materials, describe and characterize our experimental system, and use the system to demonstrate automated material detection in biological tissue.