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Publications [#282304] of Wanda K. Neu
Papers Published
- Krassowska, W; Pilkington, TC; Ideker, RE, The closed form solution to the periodic core-conductor model using asymptotic analysis.,
Ieee Transactions on Bio Medical Engineering, vol. 34 no. 7
(July, 1987),
pp. 519-531 [doi]
(last updated on 2023/06/01)
Abstract: The distribution of the transmembrane potential along an infinite strand of cardiac cells generated by a point source under steady-state conditions has been calculated using the asymptotic analysis method. With the intracellular conductivity changing periodically in space, the problem can be treated as dependent upon two variables: the large-scale variable x covering the whole strand, and the small-scale variable y defined on the unit cell. The solution is given as a two-scale expansion in powers of the period length. An example, chosen to illustrate the method, is a periodic extension of the classical core-conductor model for the infinite fiber. Although the one-dimensional, steady-state fiber is the simplest possible example, asymptotic analysis is not limited to such cases.
Keywords: bioelectric potentials;cardiology;cellular biophysics;physiological models;
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