Publications [#351379] of Jichun Xie

Papers Published

1. Xie, J; Cai, TT; Maris, J; Li, H, Optimal False Discovery Rate Control for Dependent Data., Stat Interface, vol. 4 no. 4 (2011), pp. 417-430 [doi]
   (last updated on 2026/01/17)

   Abstract:
   This paper considers the problem of optimal false discovery rate control when the test statistics are dependent. An optimal joint oracle procedure, which minimizes the false non-discovery rate subject to a constraint on the false discovery rate is developed. A data-driven marginal plug-in procedure is then proposed to approximate the optimal joint procedure for multivariate normal data. It is shown that the marginal procedure is asymptotically optimal for multivariate normal data with a short-range dependent covariance structure. Numerical results show that the marginal procedure controls false discovery rate and leads to a smaller false non-discovery rate than several commonly used p-value based false discovery rate controlling methods. The procedure is illustrated by an application to a genome-wide association study of neuroblastoma and it identifies a few more genetic variants that are potentially associated with neuroblastoma than several p-value-based false discovery rate controlling procedures.