Publications [#243556] of Richard T. Durrett

Papers Published

1. Durrett, R; Schmidt, D; Schweinsberg, J, A waiting time problem arising from the study of multi-stage carcinogenesis, Annals of Applied Probability, vol. 19 no. 2 (April, 2009), pp. 676-718, Institute of Mathematical Statistics, ISSN 1050-5164 [MR2521885 (2010f:60243)], [doi]
   (last updated on 2024/08/31)

   Abstract:
   We consider the population genetics problem: how long does it take before some member of the population has m specified mutations? The case m = 2 is relevant to onset of cancer due to the inactivation of both copies of a tumor suppressor gene. Models for larger m are needed for colon cancer and other diseases where a sequence of mutations leads to cells with uncontrolled growth. © Institute of Mathematical Statistics, 2009.