Department of Mathematics
 Search | Help | Login | pdf version | printable version

Math @ Duke



Publications [#235467] of Pankaj K. Agarwal

Papers Published

  1. Wang, Y; Agarwal, PK; Brown, P; Edelsbrunner, H; Rudolph, J, Coarse and reliable geometric alignment for protein docking. (2005), pp. 64-75, ISSN 2335-6936 [15759614]
    (last updated on 2018/12/10)

    We present an efficient algorithm for generating a small set of coarse alignments between interacting proteins using meaningful features on their surfaces. The proteins are treated as rigid bodies, but the results are more generally useful as the produced configurations can serve as input to local improvement algorithms that allow for protein flexibility. We apply our algorithm to a diverse set of protein complexes from the Protein Data Bank, demonstrating the effectivity of our algorithm, both for bound and for unbound protein docking problems.
ph: 919.660.2800
fax: 919.660.2821

Mathematics Department
Duke University, Box 90320
Durham, NC 27708-0320