Publications [#243493] of Richard T. Durrett

Papers Published

1. Arkendra, DE; Ferguson, M; Sindi, S; Durrett, R, The equilibrium distribution for a generalized Sankoff-Ferretti model accurately predicts chromosome size distributions in a wide variety of species, Journal of Applied Probability, vol. 38 no. 2 (January, 2001), pp. 324-334, Cambridge University Press (CUP), ISSN 0021-9002
   (last updated on 2024/04/19)

   Abstract:
   Sankoff and Ferretti (1996) introduced several models of the evolution of chromosome size by reciprocal translocations, where for simplicity they ignored the existence of centromeres. However, when they compared the models to data on six organisms they found that their short chromosomes were too short, and their long chromosomes were too long. Here, we consider a generalization of their proportional model with explicit chromosome centromeres and introduce fitness functions based on recombination probabilities and on the length of the longest chromosome arm. We find a simple formula for the stationary distribution for our model which fits the data on chromosome lengths in many, but not all, species.