Publications [#271855] of Michael D. De Bellis

Journal Articles

1. De Bellis, MD; Keshavan, MS; Harenski, KA (2001). Anterior cingulate N-acetylaspartate/creatine ratios during clonidine treatment in a maltreated child with posttraumatic stress disorder.. Journal of Child and Adolescent Psychopharmacology, 11(3), 311-316. [11642482], [doi]
   (last updated on 2022/08/06)

   Abstract:
   Posttraumatic stress disorder in maltreated children is associated with dysregulation of biological stress systems, adverse brain development, and neuronal loss in the anterior cingulate region of the medial prefrontal cortex. A maltreated boy with posttraumatic stress disorder was followed prospectively using single voxel proton magnetic resonance spectroscopy measures of anterior cingulate N-acetylaspartate/creatine ratios, a marker of neural integrity. N-acetylaspartate/creatine ratios increased, and sleep measures improved upon symptom remission.