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Publications [#271861] of Michael D. De Bellis

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Journal Articles

  1. De Bellis, MD; Hall, J; Boring, AM; Frustaci, K; Moritz, G (2001). A pilot longitudinal study of hippocampal volumes in pediatric maltreatment-related posttraumatic stress disorder.. Biological Psychiatry, 50(4), 305-309. [11522266], [doi]
    (last updated on 2022/08/06)

    Abstract:
    BACKGROUND:Adult posttraumatic stress disorder (PTSD) is associated with decreased hippocampal volumes; however, decreased hippocampal volumes were not seen in pediatric maltreatment-related PTSD. We examined hippocampal volumes longitudinally to determine if a history of childhood traumatic stress alters hippocampal growth during puberty. METHODS:Magnetic resonance imaging was used to measure temporal lobes, amygdala, and hippocampal volumes in nine prepubertal maltreated subjects with pediatric maltreatment-related PTSD and nine sociodemographically matched healthy nonmaltreated yoked control subjects at baseline and after at least 2 years follow-up (during the later stages of pubertal development) using identical equipment and measurement methodology. RESULTS:Temporal lobe, amygdala and hippocampal volumes did not differ between groups at baseline, follow-up, or across time. CONCLUSIONS:Whereas these data are from a small sample, the results do not support hippocampal changes in pediatric maltreatment-related PTSD.


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