| Publications [#254712] of Myron L. Wolbarsht
search PubMed.Journal Articles
- Schwarzmaier, H-J; Heintzen, MP; Mueller, W; Kaufmann, R; Wolbarsht, ML (1992). Changes in optical density of vascular tissue after 308-nm excimer laser irradiation. Proceedings of SPIE - The International Society for Optical Engineering, 1642, 11-17.
(last updated on 2018/09/26)
Abstract: Ninety-six transmission spectra were obtained from autopsy specimens of healthy human abdominal aorta. Specimens were irradiated via a 900 μm fused silica fiber (contact mode) under normal saline at room temperature (21.5 ± 1.5°C) using an excimer laser (308 nm, 40 Hz, 115 ns, 57 mJ/mm2). The temperature increased at the fiber tip up to 66.8 ± 8.5°C and was monitored by a NiCrNi thermocouple. Tissue samples from untreated areas and from the thermal damage zone next to the ablation area were anayzed by microspectrophotometry (spectral range 250-800 nm, cryosections 24 μm, area measured 6/3 μ in diameter). The conclusion is, excimer laser irradiation using a high repetition rate in combination with a high output energy changes the optical properties of human vessel walls significantly.
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