Publications [#276601] of Harry S. Swartzwelder

Journal Articles

1. Swartzwelder, HS; Johnson, CT; Cooley, BC; Howell, WE; Dyer, RS (1979). Alcohol-induced alterations in hippocampal afterdischarges and afterdischarge thresholds: dose-reponse studies.. Neurobehav Toxicol, 1(4), 253-258.
   (last updated on 2024/04/24)

   Abstract:
   The hippocampal afterdischarge (AD) has been suggested as an index of toxicant-induced CNS change [1]. The present experiments report raised AD thresholds, decreased AD durations, shorter post-stimulation latencies to AD onset, decreased numbers of AD spike complexes and increased numbers of spikes/complex following alcohol administration. Results are discussed in light of single-unit data concerning alcohol effects upon hippocampal cells, and the biphasic effects of alcohol upon behavior.