Publications [#335666] of Michael S. Gaffrey

Journal Articles

1. Gaffrey, MS; Belden, AC; Luby, JL (2011). The 2-week duration criterion and severity and course of early childhood depression: implications for nosology.. Journal of affective disorders, 133(3), 537-545.
   (last updated on 2024/04/24)

   Abstract:
   

   Background

   Although validity for DSM-IV MDD symptom criteria in preschoolers has been demonstrated, whether the 2-week duration criterion is an appropriate threshold of clinical significance at this age remains unclear. The current study aimed to begin addressing this question.

   Method

   Three hundred and six preschoolers were recruited from community sites and followed longitudinally for 2 years. A subsample including healthy preschoolers (N=77) and those with MDD (N=74) were examined. The MDD group was further divided based upon meeting (DSM, N=24) or failing to meet (LimitationsA larger sample of depressed preschoolers and refined measures of duration are needed to replicate the current study.

   Results

   Preschoolers with MDD differed significantly from controls on the majority of measures examined regardless of duration status and time of assessment. Further, the DSM group significantly differed from theConclusionsDSM-IV duration criterion failed to capture all clinically affected preschoolers at baseline or confer greater predictive validity for a depression diagnosis 2 years later. Findings suggest that preschoolers meeting all DSM-IV MDD criteria except for episode duration exhibit a clinically significant form of depression and experience a 2-year MDD outcome similar to those meeting full criterion.