Publications [#385070] of Scott C. Schmidler
Papers Published
- Li, Y; Mathews, J; Schmidler, SC. "On Gibbs Sampling for Endpoint-Conditioned Neighbor-Dependent Sequence Evolution Models." Journal of Computational and Graphical Statistics (January, 2025): 1-6. [doi]
(last updated on 2026/01/16)Abstract:
In 2008, Hobolth described an algorithm for sampling paths in models of DNA sequence evolution with neighbor dependence. We show that this algorithm fails to sample the desired target distribution, and provide a simple Metropolis acceptance step correction. We also compare to a simpler Metropolis proposal, which appears to be more efficient and which we recommend instead. We demonstrate the impact of the correction on a parameter estimation problem studied in the original paper.