Papers Published

1. Shaked, NT; Zhu, Y; Badie, N; Bursac, N; Wax, A, Reflective interferometric chamber for quantitative phase imaging of biological sample dynamics., Journal of Biomedical Optics, vol. 15 no. 3 (May, 2010), pp. 030503 [doi] .
   (last updated on 2023/06/01)

   Abstract:
   We introduce a new interferometric setup for single-exposure wide-field holographic phase imaging of highly dynamic biological samples. In this setup, the interferometric signal originates from a specially designed reflective interferometric chamber (InCh), creating an off-axis interferogram on the output plane of the system. The setup only requires the InCh and a simple reflection-mode two lens imaging system, without the need for additional optical elements such as gratings in the beam path. In addition, due to the close-to-common-path geometry of the setup, phase noise is greatly reduced. We experimentally compare the inherent phase stability of the system in ambient conditions to that of a conventional interferometer. We also demonstrate use of this system for wide-field quantitative phase imaging of two different highly dynamic, optically transparent biological samples: beating myocardial cells and moving unicellular microorganisms.