publications by Adam P. Wax.
Papers Published
- Zhao, Y; Chu, KK; Wax, A, Enhanced depth penetration by dual-axis optical coherence tomography,
Progress in Biomedical Optics and Imaging Proceedings of Spie, vol. 10867
(January, 2019) [doi] .
(last updated on 2023/06/01)Abstract:
Optical imaging techniques generally offer shallow penetration depths due to high scattering in biological tissue. We have recently developed dual-axis optical coherence tomography (DA-OCT) for interferometric imaging at extended depths. By illuminating and collecting at oblique angles, multiply forward scattered photons from deeper penetration depths were favorably detected. A Monte Carlo study demonstrated a >12-fold increase in signal-to-background ratio (SBR) in skin tissue at 1 mm depth by DA-OCT. A 1300 nm DA-OCT system was designed and constructed, offering an imaging depth of up to 2 mm in skin tissue.