publications by Ashutosh Chilkoti.
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Papers Published
- Chow, D; Nunalee, ML; Lim, DW; Simnick, AJ; Chilkoti, A, Peptide-based Biopolymers in Biomedicine and Biotechnology.,
Materials science & engineering. R, Reports : a review journal, vol. 62 no. 4
(January, 2008),
pp. 125-155 [19122836], [doi] .
(last updated on 2024/04/24)Abstract:
Peptides are emerging as a new class of biomaterials due to their unique chemical, physical, and biological properties. The development of peptide-based biomaterials is driven by the convergence of protein engineering and macromolecular self-assembly. This review covers the basic principles, applications, and prospects of peptide-based biomaterials. We focus on both chemically synthesized and genetically encoded peptides, including poly-amino acids, elastin-like polypeptides, silk-like polymers and other biopolymers based on repetitive peptide motifs. Applications of these engineered biomolecules in protein purification, controlled drug delivery, tissue engineering, and biosurface engineering are discussed.