publications by Mark W. Dewhirst.


Papers Published

  1. Samulski, T.V. and Grant, W.J. and Oleson, J.R. and Leopold, K.A. and Dewhirst, M.W. and Vallario, P. and Blivin, J., Clinical experience with a multi-element ultrasonic hyperthermia system: analysis of treatment temperatures, Int. J. Hyperth. (UK), vol. 6 no. 5 , pp. 909 - 22 .
    (last updated on 2007/04/14)

    Abstract:
    A summary of tumour temperature data obtained from 31 patients who underwent 147 hyperthermia treatments with the Sonotherm 1000 ultrasonic system is presented. The treatment goal was to achieve a minimum of 42.0°C in tumour for 60 min duration with normal tissues remaining below 43.0°C. In 83% of treatments at least one measured tumour temperature reached or exceeded 42.0°C at some time during the treatment. Nineteen per cent of these treatments had a time- and spatial-averaged temperature (measured in tumour)⩾42.0°C. A variety of anatomical sites were treated and these were grouped into four categories: groin/trunk, axilla, breast/chest wall and head/neck. Measured temperatures in tumours located in the groin and trunk sites were significantly higher (22%⩾42°C) than other locations. The head and neck treatment temperatures were significantly lower (8% of measured points ⩾42°C)

    Keywords:
    biomedical ultrasonics;biothermics;radiation therapy;

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