search www.ncbi.nlm.nih.gov.

Papers Published

1. JR MacFall, HC Charles, RD Black, H Middleton, JC Swartz, B Saam, B Driehuys, C Erickson, W Happer, GD Cates, GA Johnson, CE Ravin, Human lung air spaces: potential for MR imaging with hyperpolarized He-3., Radiology, UNITED STATES, vol. 200 no. 2 (August, 1996), pp. 553-8 .
   (last updated on 2005/08/03)

   Abstract:
   Two healthy volunteers who had inhaled approximately 0.75 L of laser-polarized helium-3 gas underwent magnetic resonance imaging at 1.5 T with fast gradient-echo pulse sequences and small flip angles ( < 10 degrees). Thick-section (20 mm) coronal images, time-course data (30 images collected every 1.8 seconds), and thin-section (6 mm) images were acquired. Subjects were able to breathe the gas (12% polarization) without difficulty. Thick-section images were of good quality and had a signal-to-noise ratio (S/N) of 32:1 near the surface coil and 16:1 farther away. The time images showed regional differences, which indicated potential value for quantitation. High-resolution images showed greater detail and a S/N of approximately 6:1.

   Keywords:
   Adult • Helium • Humans • Image Enhancement • Isotopes • Lung • Magnetic Resonance Imaging • Male • Middle Aged • anatomy & histology* • diagnostic use* • instrumentation • methods • methods*