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Papers Published

1. Johnson, GA; Cofer, GP; Gewalt, SL; Hedlund, LW, Morphologic phenotyping with MR microscopy: the visible mouse., Radiology, vol. 222 no. 3 (March, 2002), pp. 789-793 [11867802], [doi] .
   (last updated on 2025/02/12)

   Abstract:
   A method for rapid morphologic phenotyping is demonstrated by using magnetic resonance microscopy. Whole fixed C57BL/6J mice were imaged at 110-microm isotropic resolution; limited volumes of the intact specimen, at 50-microm isotropic resolution; and isolated organs, at 25-microm isotropic resolution. The three-dimensional imaging technique was applied to uricase knockout mice to demonstrate the method for the evaluation of morphologic phenotype.

   Keywords:
   Animals • Contrast Media • Gadolinium DTPA • Imaging, Three-Dimensional* • Magnetic Resonance Imaging • Male • Mice • Mice, Inbred C57BL • Mice, Knockout • Microscopy • Phenotype • Urate Oxidase • administration & dosage • anatomy & histology* • diagnostic use • genetics • methods*