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Papers Published

1. Bone, SN; Johnson, GA; Thompson, MB, Three-dimensional magnetic resonance microscopy of the developing chick embryo., Invest Radiol, vol. 21 no. 10 (October, 1986), pp. 782-787 [Gateway.cgi], [doi] .
   (last updated on 2025/02/14)

   Abstract:
   Magnetic resonance imaging microscopy was performed on live chick embryos. A combination of high gradient strength (0.47 mT/cm), special purpose radiofrequency coils and 3-dimensional Fourier imaging was used to obtain images with effective thickness of 1.25 mm and pixel dimensions as small as 200 mu in the live chick embryo. The signal-to-noise ratio was sufficient to allow unequivocal identification of the individual chambers of the heart, spinal cord, ventricles in the brain, and vascular structures in the liver of a live 11-day embryo. Anatomical assignment was accomplished with the aid of correlated histologic sections. Because there are no external landmarks, the plane of imaging is frequently oblique, making the 3-dimensional acquisition particularly useful.