Papers Published

1. HP Erickson, The FtsZ protofilament and attachment of ZipA--structural constraints on the FtsZ power stroke., Current opinion in cell biology, United States, vol. 13 no. 1 (February, 2001), pp. 55-60 .
   (last updated on 2009/02/12)

   Abstract:
   Bacterial cell division protein FtsZ forms protofilaments in vitro that can shift from a straight to a curved conformation. The inside of the curved protofilaments, which corresponds to the carboxyl terminus, should face the center of the cell as curvature increases during constriction of the Z-ring. ZipA, a membrane-tethered division protein, binds to a highly conserved short peptide on the carboxyl terminus of FtsZ. A model is proposed here for how membrane-bound ZipA can reach around the FtsZ protofilament to bind the carboxy-terminal peptide, which faces away from the membrane.

   Keywords:
   Amino Acid Sequence • Bacterial Proteins • Carrier Proteins • Cell Cycle Proteins • Cell Division • Cytoskeletal Proteins* • Escherichia coli Proteins* • Models, Molecular • Molecular Sequence Data • Protein Conformation • Structure-Activity Relationship • chemistry* • physiology • physiology*