Papers Published

1. Applegate, B.E. and Changhuei Yang and Rollins, A.M. and Izatt, J.A., Polarization-resolved second-harmonic-generation optical coherence tomography in collagen, Opt. Lett. (USA), vol. 29 no. 19 (2004), pp. 2252 - 4 [OL.29.002252] .
   (last updated on 2007/04/13)

   Abstract:
   We describe a novel imaging technique, second-harmonic-generation optical coherence tomography (SHOCT). This technique combines the spatial resolution and depth penetration of optical coherence tomography (OCT) with the molecular sensitivity of second-harmonic-generation spectroscopy. As a consequence of the coherent detection required for OCT, polarization-resolved images arise naturally. We demonstrate this new technique on a skin sample from the belly of Icelandic salmon, acquiring polarization-resolved SHOCT and OCT images simultaneously

   Keywords:
   biomedical optical imaging;image resolution;light polarisation;molecular biophysics;optical harmonic generation;optical tomography;proteins;skin;