Papers Published

1. Trayanova, N; Krassowska, W, Virtual electrode effects in a bidomain model with electroporating membrane, Annual International Conference of the Ieee Engineering in Medicine and Biology Proceedings, vol. 17 no. 1 (December, 1995), pp. 255-256 [IEMBS.1995.575097] .
   (last updated on 2023/06/01)

   Abstract:
   This study examines the effects of electroporation in a computer simulation of the response of a two-dimensional slice of myocardium to electrical stimulation. The multicellular, syncytial cardiac tissue is represented by the bidomain model. Electroporation is incorporated in the membrane behavior through changes in the membrane conductance. The conductance increases at a rate that depends exponentially on the square of the transmembrane potential. The time course of the shock-induced transmembrane potential distribution in a slice of myocardium with electroporating membrane is compared to the one without electroporation. The differences in magnitude and spatial extent of the regions of direct membrane polarization (the virtual electrodes) are identified.

   Keywords:
   Tissue;Electric field effects;Computer simulation;Electric resistance;Bioelectric potentials;Polarization;Mathematical models;Shock waves;Electrodes;Current density;Electric current distribution;