Papers Published

1. Su, F; Chakrabarty, K, Defect tolerance for gracefully-degradable microfluidics-based biochips, Proceedings of the Ieee Vlsi Test Symposium (December, 2005), pp. 321-326, IEEE Comput. Soc [mostRecentIssue.jsp], [doi] .
   (last updated on 2022/12/30)

   Abstract:
   Defect tolerance is an important design consideration for microfluidics-based biochips that are used for safety-critical applications. We propose a defect tolerance methodology based on graceful degradation and dynamic reconfiguration. We first introduce tile-based biochip architecture, which is scalable for large-scale bioassays. A clustered defect model is used to evaluate the graceful degradation method for tile-based biochips. The proposed schemes ensure that the bioassays mapped to a droplet-based microfluidic array during design can be executed on a defective biochip through operation rescheduling and/or resource rebinding. Real-life biochemical procedures, namely polymerase chain reaction (PCR) and multiplexed in-vitro diagnostics on human physiological fluids, are used to evaluate the proposed defect tolerance schemes. © 2005 IEEE.