Publications by Krishnendu Chakrabarty.

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Papers Published

  1. Su, F; Ozev, S; Chakrabarty, K, Ensuring the operational health of droplet-based microelectrofluidic biosensor systems, Ieee Sensors Journal, vol. 5 no. 4 (August, 2005), pp. 763-772, Institute of Electrical and Electronics Engineers (IEEE) [doi] .
    (last updated on 2022/12/30)

    Abstract:
    Recent events have heightened the need for fast, accurate, and reliable biological/chemical sensor systems for critical loca tions. As droplet-based microelectrofluidic sensor systems become widespread in these safety-critical biomedical applications, reliability emerges as a critical performance parameter. In order to ensure the operational health of such safety-critical systems, they need to be monitored for defects, not only after manufacturing, but also during in-field operation. In this paper, we present a cost-effective concurrent test methodology for droplet-based microelectrofluidic systems. We present a classification of catastrophic and parametric faults in such systems and show how faults can be detected by electrostatically controlling and tracking droplet motion. We then present a fault simulation approach based on tolerance analysis using Monte-Carlo simulation to characterize the impact of parameter variations on system performance. Finally, we present experimental results on a droplet-based microelectrofluidic system for a real-time polymerase chain reaction application. © 2005 IEEE.