Papers Published

1. Su, F; Chakrabarty, K, Defect tolerance based on graceful degradation and dynamic reconfiguration for digital microfluidics-based biochips, Ieee Transactions on Computer Aided Design of Integrated Circuits and Systems, vol. 25 no. 12 (December, 2006), pp. 2944-2953, Institute of Electrical and Electronics Engineers (IEEE) [doi] .
   (last updated on 2022/12/30)

   Abstract:
   Defect tolerance is an important design consideration for microfluidics-based biochips that are used for safety-critical applications. The authors propose a defect-tolerance methodology based on graceful degradation and dynamic reconfiguration. A tile-based biochip architecture is first introduced, which is scalable for large-scale bioassays. A clustered defect model is used to evaluate the graceful-degradation method for tile-based biochips. The proposed schemes ensure that the bioassays mapped to a droplet-based microfluidic array during design can be executed on a defective biochip through operation rescheduling and/or resource rebinding. Real-life biochemical procedures, namely polymerase chain reaction and multiplexed in vitro diagnostics on human physiological fluids, are used to evaluate the proposed defect-tolerance schemes. © 2006 IEEE.