Publications by Krishnendu Chakrabarty.

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Papers Published

  1. Ibrahim, M; Chakrabarty, K, Digital-microfluidic biochips for quantitative analysis: Bridging the Gap between microfluidics and microbiology, Proceedings of the 2017 Design, Automation and Test in Europe, Date 2017 (May, 2017), pp. 1787-1792, IEEE [doi] .
    (last updated on 2022/12/30)

    Abstract:
    Digital-microfluidics technology has shown considerable promise for advancing sample preparation and point-of-care diagnostics; therefore, it has the potential to transform microbiology and biochemistry research. Over the past decade, a number of microfluidics design-automation techniques have been developed for on-chip droplet manipulation. However, these methods overlook the myriad complexities of biomolecular protocols and they have yet to make a significant impact in biochemistry/microbiology research. A paradigm shift in biochip design automation and a 'phase transition' in research are clearly needed to bridge this gap between microfluidics and microbiology. In this paper, we explain how researchers from design-automation and embedded systems can play a key role in this transition. We present a new synthesis flow that uses realistic models of biomolecular protocols and cyberphysical adaptation to address real-world microbiology applications. We also present a list of metrics that can be used for the assessment of designautomation techniques for microbiology applications.