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| Publications of Emily Cherenack :chronological alphabetical combined listing:%% Journal Articles @article{fds357507, Author = {Cherenack, EM and Sikkema, KJ}, Title = {Puberty- and Menstruation-Related Stressors Are Associated with Depression, Anxiety, and Reproductive Tract Infection Symptoms Among Adolescent Girls in Tanzania.}, Journal = {International Journal of Behavioral Medicine}, Year = {2021}, Month = {June}, url = {http://dx.doi.org/10.1007/s12529-021-10005-1}, Abstract = {<h4>Background</h4>Puberty and menstruation are significant stressors for adolescent girls and young women in low-resource settings in sub-Saharan Africa. However, little is known about the impact of these stressors on girls' mental health and reproductive health.<h4>Methods</h4>In 2018, a cross-sectional self-report survey was conducted with 581 adolescent girls and young women between 13 to 21 years old who had reached menarche and were attending secondary school in Moshi, Tanzania. Structural equation modeling was used to examine the relationships of puberty-related stressors and menstruation-related stressors (menstrual deficits, movement/activity difficulties, and menstrual symptoms) to depression, anxiety, and the likelihood of reporting reproductive tract infection (RTI) symptoms.<h4>Results</h4>Puberty-specific stressors, menstrual symptoms, and menstrual deficits were associated with depression and anxiety. Movement/activity difficulties were associated with anxiety. Increases in menstrual symptoms, menstrual deficits, puberty stressors, and depression were associated with an increased likelihood of reporting a lifetime RTI. However, the relationship of puberty stressors and depression with RTIs was no longer significant in two of three models after correcting for Type I error.<h4>Conclusions</h4>Overall, puberty- and menstruation-related stressors were associated with mental health and symptoms of reproductive tract infections. This suggests there is an important relationship between stressors specific to adolescent girls and young women during puberty, mental health, and reproductive health. There is a need for adolescent-tailored interventions to reduce the negative impact of stressors among girls transitioning through puberty in sub-Saharan Africa.}, Doi = {10.1007/s12529-021-10005-1}, Key = {fds357507} } @article{fds357455, Author = {Tapia, GR and Glynn, TR and Miller, C and Manuzak, JA and Broedlow, CA and Mcgaugh, A and Cherenack, EM and Bauermeister, JA and Grov, C and Dilworth, SE and Parisi, R and Martinez, D and Klatt, NR and Carrico, AW}, Title = {Syndemics and pre-exposure prophylaxis are independently associated with rectal immune dysregulation in sexual minority men.}, Journal = {Aids}, Year = {2021}, Month = {March}, url = {http://dx.doi.org/10.1097/qad.0000000000002866}, Abstract = {<h4>Objective</h4>Syndemic conditions have been linked to engagement in receptive condomless anal sex (CAS) and HIV seroconversion. However, little is known about the biological pathways whereby syndemics could amplify vulnerability to HIV and other sexually transmitted infections (STIs).<h4>Design</h4>HIV-negative sexual minority men (i.e., gay, bisexual, and other men who have sex with men) were recruited from four STI clinics in South Florida for a cross-sectional study.<h4>Methods</h4>Participants completed assessments for four syndemic conditions: depression, post-traumatic stress disorder, hazardous alcohol use, and any stimulant use (i.e., any self-reported use or reactive urine toxicology results). Cytokine and chemokine levels were measured using LEGENDplex from the rectal swabs of 92 participants reporting receptive CAS and no antibiotic use in the past three months.<h4>Results</h4>After controlling for age, race/ethnicity, pre-exposure prophylaxis (PrEP) use, and number of receptive CAS partners, a greater number of syndemic conditions was associated with higher levels of rectal cytokines/chemokines relevant to immune activation, inflammation, and the expansion and maintenance of T-helper 17 target cells, including rectal interferon-gamma (β = 0.22; p = 0.047), CXCL-8 (β = 0.24; p = 0.025), and interleukin-23 (β = 0.22; p = 0.049). Elevations in rectal cytokine or chemokine levels were most pronounced among participants experiencing two or more syndemic conditions compared to those experiencing no syndemic conditions. PrEP use was independently associated with elevations in multiple rectal cytokines/chemokines.<h4>Conclusions</h4>Syndemic conditions could increase biological vulnerability to HIV and other STIs in sexual minority men by potentiating rectal immune dysregulation.}, Doi = {10.1097/qad.0000000000002866}, Key = {fds357455} } @article{fds357456, Author = {Knettel, B and Corrigan, K and Cherenack, E and Ho, N and Carr, S and Cahill, J and Chino, J and Ubel, P and Watt, M and Suneja, G}, Title = {HIV, cancer, and coping: The cumulative burden of a cancer diagnosis among people living with HIV.}, Journal = {J Psychosoc Oncol}, Pages = {1-14}, Year = {2021}, Month = {January}, url = {http://dx.doi.org/10.1080/07347332.2020.1867691}, Abstract = {OBJECTIVES: People living with HIV (PLWH) have increased risk for cancer and worse cancer-specific survival. We explored the emotional burden of cancer and HIV as a potential driver of cancer mortality. RESEARCH APPROACH: Semi-structured qualitative interviews with PLWH and cancer. PARTICIPANTS: 27 PLWH who had either completed cancer treatment, were currently undergoing treatment, or experienced challenges in completing treatment. METHODOLOGICAL APPROACH: An inductive qualitative approach using the constant comparative method. FINDINGS: Participants drew strong parallels between being diagnosed with HIV and cancer. Many described HIV-related stigma that hindered social support. Cancer treatment side effects were a major challenge, impacting treatment adherence for both cancer and HIV. IMPLICATIONS FOR PSYCHOSOCIAL PROVIDERS: There is a need for convenient, affordable, and visible services to support PLHIV as they navigate cancer care. Services should be tailored to the unique needs of this population by addressing HIV-related stigma, building social support, and fostering resilience.}, Doi = {10.1080/07347332.2020.1867691}, Key = {fds357456} } @article{fds357457, Author = {Knettel, BA and Cherenack, EM and Friis, EA}, Title = {Examining causal attributions for depression, alcohol use disorder, and schizophrenia in a diverse sample of international students at U.S. universities.}, Journal = {Journal of American College Health : J of Ach}, Pages = {1-8}, Year = {2021}, Month = {January}, url = {http://dx.doi.org/10.1080/07448481.2020.1846046}, Abstract = {<h4>Objectives</h4>International students face increased vulnerability for mental health challenges, but underutilize counseling compared to their domestic peers. We examined beliefs regarding the causes of mental illness, known as attributions, which may impact treatment-seeking and stigma. <b>Participants:</b> Surveys were collected from 680 international students at U.S. universities. <b>Methods:</b> We sent invitations to a computer-based survey disseminated via international student email lists. The survey explored mental health attributions for depression, alcohol use disorder, and schizophrenia. <b>Results:</b> Attributions differed significantly by disorder. Depression and alcohol use were attributed to social stress and perceived as controllable and influenced by personal weakness and lifestyle choices. Schizophrenia was often attributed to hereditary/biological causes. Differences also emerged based on the participants' acculturation, region of origin, and religiosity. <b>Conclusions:</b> Attributions influence perceptions of mental illness and may lead to stigma. Providers should incorporate discussions of attribution in student outreach and counseling to address potential impacts on care-seeking.}, Doi = {10.1080/07448481.2020.1846046}, Key = {fds357457} } @article{fds357458, Author = {Cherenack, EM and Tolley, EE and Kaaya, S and Headley, J and Baumgartner, JN}, Title = {Depression and Sexual Trauma Among Adolescent Girls and Young Women in HIV-Prevention Research in Tanzania.}, Journal = {Maternal and Child Health Journal}, Volume = {24}, Number = {5}, Pages = {620-629}, Year = {2020}, Month = {May}, url = {http://dx.doi.org/10.1007/s10995-020-02888-5}, Abstract = {<h4>Purpose</h4>Clinical trials are necessary to test HIV-prevention strategies among adolescent girls and young women in sub-Saharan Africa. Psychosocial risk factors that increase girls' and young women's vulnerability for HIV may also impact their experiences in clinical trials. A better understanding of psychosocial risks among girls and young women enrolled in HIV-prevention research is needed. This analysis explores depression and sexual trauma among adolescent girls and young women enrolled in a mock microbicide trial in Tanzania.<h4>Methods</h4>We collected cross-sectional data from 135 HIV-negative adolescent girls and young women between 15 and 21 in Dar es Salaam, Tanzania enrolled in a mock microbicide trial. Depression, sexual behavior, and sexual trauma were measured. Sexual trauma and demographic variables were entered into a multivariate binomial logistic regression model predicting depression.<h4>Findings</h4>Overall, 27% of participants had moderate-to-severe depression. The most commonly endorsed items were anhedonia (lack of interest/pleasure) and low mood, which were reported by 78% of participants. Thoughts of suicide or self-harm were endorsed by 17% of participants. Coerced/forced first sex was reported by 42% of participants. Participants reporting coerced/forced first sex had 3.16 times the likelihood of moderate-to-severe depression.<h4>Conclusions</h4>Depression and coerced/forced sex were common among participants in an HIV-prevention mock clinical trial in Tanzania. When enrolling adolescent girls and young women in HIV-prevention trials in sub-Saharan Africa, our research suggests the need for a trauma-informed approach, referrals for trauma and depression, and interventions that address the impact of depression and trauma on HIV prevention, clinical trial adherence, and clinical outcomes.}, Doi = {10.1007/s10995-020-02888-5}, Key = {fds357458} } @article{fds357459, Author = {Cherenack, EM and Rubli, J and Dow, DE and Sikkema, KJ}, Title = {Sexual Risk Behaviors and Menstrual and Intravaginal Practices Among Adolescent Girls and Young Women in Tanzania: A Cross-Sectional, School-Based Study}, Journal = {International Journal of Sexual Health}, Volume = {32}, Number = {4}, Pages = {394-407}, Year = {2020}, Month = {January}, url = {http://dx.doi.org/10.1080/19317611.2020.1821861}, Abstract = {Objectives: Objectives were to describe menstrual and intravaginal practices and sexual risk behaviors among adolescent girls and young women (AGYW) in Tanzania. Methods: A cross-sectional survey was conducted in secondary schools in Tanzania. Data on menstrual practices (e.g., product use), intravaginal practices (e.g., douching), and sexual risk were analyzed using chi-square and loglinear analyses. Results: Menstrual risk practices were common. Sexual risk behaviors and intravaginal practices were high among AGYW reporting sexual debut. Conclusions: High levels of menstrual, intravaginal, and sexual risk practices highlight the need to improve menstrual, sexual, and intravaginal practices, particularly among sexually active AGYW.}, Doi = {10.1080/19317611.2020.1821861}, Key = {fds357459} } @article{fds332042, Author = {Cherenack, EM and Sikkema, KJ and Watt, MH and Hansen, NB and Wilson, PA}, Title = {Avoidant Coping Mediates the Relationship Between Self-Efficacy for HIV Disclosure and Depression Symptoms Among Men Who Have Sex with Men Newly Diagnosed with HIV.}, Journal = {Aids and Behavior}, Volume = {22}, Number = {10}, Pages = {3130-3140}, Year = {2018}, Month = {October}, url = {http://dx.doi.org/10.1007/s10461-018-2036-2}, Abstract = {HIV diagnosis presents a critical opportunity to reduce secondary transmission, improve engagement in care, and enhance overall well-being. To develop relevant interventions, research is needed on the psychosocial experiences of newly diagnosed individuals. This study examined avoidant coping, self-efficacy for HIV disclosure decisions, and depression among 92 newly diagnosed men who have sex with men who reported recent sexual risk behavior. It was hypothesized that avoidant coping would mediate the relationship between self-efficacy and depression. Cross-sectional surveys were collected from participants 3 months after HIV diagnosis. To test for mediation, multiple linear regressions were conducted while controlling for HIV disclosure to sexual partners. Self-efficacy for HIV disclosure decisions showed a negative linear relationship to depression symptoms, and 99% of this relationship was mediated by avoidant coping. The index of mediation of self-efficacy on depression indicated a small-to-medium effect. Higher self-efficacy was related to less avoidant coping, and less avoidant coping was related to decreased depression symptoms, all else held constant. These findings highlight the role of avoidant coping in explaining the relationship between self-efficacy for HIV disclosure decisions and depression.}, Doi = {10.1007/s10461-018-2036-2}, Key = {fds332042} } @article{fds331648, Author = {Sikkema, KJ and Mulawa, MI and Robertson, C and Watt, MH and Ciya, N and Stein, DJ and Cherenack, EM and Choi, KW and Kombora, M and Joska, JA}, Title = {Improving AIDS Care After Trauma (ImpACT): Pilot Outcomes of a Coping intervention Among HIV-Infected Women with Sexual Trauma in South Africa.}, Journal = {Aids and Behavior}, Volume = {22}, Number = {3}, Pages = {1039-1052}, Year = {2018}, Month = {March}, url = {http://dx.doi.org/10.1007/s10461-017-2013-1}, Abstract = {Improving AIDS Care after Trauma (ImpACT), a coping intervention for HIV-infected women with sexual abuse histories, was evaluated for feasibility and potential efficacy in a public clinic in Cape Town, South Africa. Sixty-four participants were enrolled prior to starting antiretroviral therapy (ART). After completing baseline assessments, participants were randomly assigned to standard of care (SoC: three adherence counseling sessions) or ImpACT (SoC plus four individual and three group sessions). Participants completed assessments at 3 months (after individual sessions) and 6 months post-baseline. In exploratory analysis of primary outcomes, ImpACT participants, compared to SoC, reported greater reductions in avoidance and arousal symptoms of PTSD and greater increases in ART adherence motivation at 3 months. Clinically significant decreases in overall PTSD symptoms were also demonstrated at 3 months. These effects continued as trends at the 6-month assessment, in addition to increases in social/spiritual coping. In analysis of secondary outcomes, high levels of non-adherence to ART and poor care engagement were evident at 6 months, with no differences between study arms. A trauma-focused, culturally-adapted individual intervention delivered by a non-specialist in the HIV care setting is feasible and acceptable. Preliminary findings suggest ImpACT has potential to reduce PTSD symptoms and increase ART adherence motivation, but a more intensive intervention may be needed to improve and maintain care engagement among this population.<h4>Trial registration</h4>ClinicalTrials.gov NCT02223390.}, Doi = {10.1007/s10461-017-2013-1}, Key = {fds331648} } @article{fds335641, Author = {Carrico, AW and Cherenack, EM and Roach, ME and Riley, ED and Oni, O and Dilworth, SE and Shoptaw, S and Hunt, P and Roy, S and Pallikkuth, S and Pahwa, S}, Title = {Substance-associated elevations in monocyte activation among methamphetamine users with treated HIV infection.}, Journal = {Aids}, Volume = {32}, Number = {6}, Pages = {767-771}, Year = {2018}, Month = {March}, url = {http://dx.doi.org/10.1097/qad.0000000000001751}, Abstract = {OBJECTIVE:Microbial translocation and monocyte activation predict mortality in treated HIV. We examined whether substance use independently contributes to these pathophysiologic processes. DESIGN:Cross-sectional study at baseline for a randomized controlled trial. METHODS:HIV-positive, methamphetamine-using MSM with undetectable HIV viral load (less than 40 copies/ml) were enrolled. We examined if plasma biomarkers of monocyte activation and intestinal barrier integrity were associated with the following: reactive urine toxicology results (Tox+) for stimulants (i.e., methamphetamine or cocaine) and substance use severity measured by the Addiction Severity Index. Multiple linear regression models adjusted for age, antiretroviral therapy regimen, CD4 T-cell count, interleukin-6, and alcohol use severity. RESULTS:The sample of 84 virally suppressed MSM had a median CD4 T-cell count of 645 cells/μl. Those who were Tox+ for stimulants displayed higher soluble CD14 (sCD14) levels (2087 versus 1801 ng/ml; P = 0.009), and this difference remained significant after adjusting for covariates (standardized beta = 0.23, P = 0.026). Greater substance use severity was also independently associated with higher sCD14 after adjusting for covariates (standardized beta = 0.29, P = 0.013). Being Tox+ for stimulants and substance use severity were not associated with soluble CD163 (sCD163) or intestinal fatty acid binding protein (iFABP) levels (P > 0.05). CONCLUSIONS:Monocyte activation is one plausible mechanism by which stimulant use may increase clinical HIV progression.}, Doi = {10.1097/qad.0000000000001751}, Key = {fds335641} } @article{fds330403, Author = {Wilson, PA and Cherenack, EM and Jadwin-Cakmak, L and Harper, GW and Adolescent Medicine Trials Network for HIV/AIDS Interventions}, Title = {Selection and Evaluation of Media for Behavioral Health Interventions Employing Critical Media Analysis.}, Journal = {Health Promotion Practice}, Volume = {19}, Number = {1}, Pages = {145-156}, Year = {2018}, Month = {January}, url = {http://dx.doi.org/10.1177/1524839917711384}, Abstract = {Although a growing number of psychosocial health promotion interventions use the critical analysis of media to facilitate behavior change, no specific guidelines exist to assist researchers and practitioners in the selection and evaluation of culturally relevant media stimuli for intervention development. Mobilizing Our Voices for Empowerment is a critical consciousness-based health enhancement intervention for HIV-positive Black young gay/bisexual men that employs the critical analysis of popular media. In the process of developing and testing this intervention, feedback on media stimuli was collected from youth advisory board members (n = 8), focus group participants (n = 19), intervention participants (n = 40), and intervention facilitators (n = 6). A thematic analysis of qualitative data resulted in the identification of four key attributes of media stimuli and participants' responses to media stimuli that are important to consider when selecting and evaluating media stimuli for use in behavioral health interventions employing the critical analysis of media: comprehension, relevance, emotionality, and action. These four attributes are defined and presented as a framework for evaluating media, and adaptable tools are provided based on this framework to guide researchers and practitioners in the selection and evaluation of media for similar interventions.}, Doi = {10.1177/1524839917711384}, Key = {fds330403} } @article{fds318680, Author = {Cherenack, EM and Wilson, PA and Kreuzman, AM and Price, GN and Adolescent Medicine Trials Network for HIV/AIDS Interventions}, Title = {The Feasibility and Acceptability of Using Technology-Based Daily Diaries with HIV-Infected Young Men Who have Sex with Men: A Comparison of Internet and Voice Modalities.}, Journal = {Aids and Behavior}, Volume = {20}, Number = {8}, Pages = {1744-1753}, Year = {2016}, Month = {August}, url = {http://dx.doi.org/10.1007/s10461-016-1302-4}, Abstract = {This study delivered a daily diary to 67 HIV-infected men who have sex with men (MSM) between 16 and 24 years old for 66 days to measure HIV-risk behaviors and other psychosocial variables via two diary modalities: internet (accessible via any web-enabled device) and voice (accessible via telephone). Participants were randomized to complete one diary modality for 33 days before switching to the second modality for 33 days. The study was implemented in three urban HIV health care centers in the United States where participants were receiving services. Through diary data and qualitative interview data, we examined the feasibility and acceptability of the dairies and identified barriers and facilitators of dairy compliance. Results show high participant retention in the daily diary (93.4 %) and high compliance for the number of dairies completed (72.4 %). Internet diaries were preferred by 92 % of participants and completed at a significantly higher rate (77.5 %) than voice diaries (67.7 %). Facilitators included opportunities for self-reflection and cathartic sharing, monetary compensation, relationships with study staff, and daily reminders. Barriers included being busy or not having privacy at the time of reminders, forgetting, and falling asleep. Participants also described barriers and facilitators unique to each modality. Overall, both modalities were feasible and acceptable for use with our sample of HIV-infected MSM.}, Doi = {10.1007/s10461-016-1302-4}, Key = {fds318680} } @article{fds318681, Author = {Wilson, PA and Meyer, IH and Antebi-Gruszka, N and Boone, MR and Cook, SH and Cherenack, EM}, Title = {Profiles of Resilience and Psychosocial Outcomes among Young Black Gay and Bisexual Men.}, Journal = {American Journal of Community Psychology}, Volume = {57}, Number = {1-2}, Pages = {144-157}, Year = {2016}, Month = {March}, url = {http://dx.doi.org/10.1002/ajcp.12018}, Abstract = {Young Black gay/bisexual men (YBGBM) are affected by contextual stressors-namely syndemic conditions and minority stress-that threaten their health and well-being. Resilience is a process through which YBGBM achieve positive psychosocial outcomes in the face of adverse conditions. Self-efficacy, hardiness and adaptive coping, and social support may be important resilience factors for YBGBM. This study explores different profiles of these resilience factors in 228 YBGBM in New York City and compares profiles on psychological distress, mental health, and other psychosocial factors. Four profiles of resilience were identified: (a) Low self-efficacy and hardiness/adaptive coping (23.5%); (b) Low peer and parental support (21.2%); (c) High peer support, low father support (34.5%); and (d) High father and mother support, self-efficacy, and hardiness/adaptive coping (20.8%). YBGBM in profile 1 scored markedly higher on distress (d = .74) and lower on mental health functioning (d = .93) compared to men in the other profiles. Results suggest that self-efficacy and hardiness/adaptive coping may play a more important role in protecting YBGBM from risks compared to social support and should be targeted in interventions. The findings show that resilience is a multidimensional construct and support the notion that there are different patterns of resilience among YBGBM.}, Doi = {10.1002/ajcp.12018}, Key = {fds318681} } @article{fds318682, Author = {Boone, MR and Cherenack, EM and Wilson, PA and ATN 086/106 Protocol Team}, Title = {Self-Efficacy for Sexual Risk Reduction and Partner HIV Status as Correlates of Sexual Risk Behavior Among HIV-Positive Adolescent Girls and Women.}, Journal = {Aids Patient Care and Stds}, Volume = {29}, Number = {6}, Pages = {346-353}, Year = {2015}, Month = {June}, url = {http://dx.doi.org/10.1089/apc.2014.0175}, Abstract = {Little is known about the correlates of sexual risk behavior among HIV-positive adolescent girls and women in the United States. This study investigates two potential factors related to unprotected vaginal and anal intercourse (UVAI) that have yet to be thoroughly studied in this group: self-efficacy for sexual risk reduction and partner HIV status. Data was analyzed from 331 HIV-positive adolescent girls and women between 12 and 24 years old who reported vaginal and/or anal intercourse with a male partner in the past 3 months at fifteen sites across the United States. Results show that overall self-efficacy (B=-0.15, p=0.01), self-efficacy to discuss safe sex with one's partner (B=-0.14, p=0.01), and self-efficacy to refuse unsafe sex (B=-0.21, p=0.01) are related to UVAI episodes. Participants with only HIV-positive partners or with both HIV-positive and HIV-negative partners showed a trend towards higher percentages of UVAI episodes compared to participants with only HIV-negative partners (F(2, 319)=2.80, p=0.06). These findings point to the importance of including self-efficacy and partner HIV status in risk-reduction research and interventions developed for HIV-positive adolescent girls and young women.}, Doi = {10.1089/apc.2014.0175}, Key = {fds318682} } @article{fds318683, Author = {Wilson, PA and Nanin, J and Amesty, S and Wallace, S and Cherenack, EM and Fullilove, R}, Title = {Using syndemic theory to understand vulnerability to HIV infection among Black and Latino men in New York City.}, Journal = {Journal of Urban Health : Bulletin of the New York Academy of Medicine}, Volume = {91}, Number = {5}, Pages = {983-998}, Year = {2014}, Month = {October}, url = {http://dx.doi.org/10.1007/s11524-014-9895-2}, Abstract = {HIV is a public health crisis that disproportionately affects Black and Latino men. To understand this crisis, syndemic theory, which takes into account multiple interrelated epidemics, should be used. A syndemic is "two or more afflictions, interacting synergistically, contributing to excess burden of disease in a population." Vulnerability to HIV among Black and Latino men is increased as structural, social, and biological factors interact in the context of social marginalization. In New York City, Black and Latino men experience a syndemic of HIV/AIDS, substance abuse, trauma, incarceration, and poverty; however, current research has yet to fully identify the mechanisms of resilience that may reduce the negative impact of a syndemic or explore the potential adaptive functions of individual-level risk behaviors. To understand HIV risk as part of a syndemic and address HIV prevention in Black and Latino men, we propose the following: (1) the use of complex systems analysis, ethnography, and other mixed-methods approaches to observe changes in relations among social conditions and disease; (2) multidisciplinary and inter-institution collaboration; and (3) involvement of public health practitioners and researchers from diverse and underrepresented backgrounds.}, Doi = {10.1007/s11524-014-9895-2}, Key = {fds318683} } | |
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