Publications of Valeria Caruso    :chronological  alphabetical  combined listing:

%% Journal Articles   
@article{fds335640,
   Author = {Caruso, VC and Mohl, JT and Glynn, C and Lee, J and Willett, SM and Zaman,
             A and Ebihara, AF and Estrada, R and Freiwald, WA and Tokdar, ST and Groh,
             JM},
   Title = {Single neurons may encode simultaneous stimuli by switching
             between activity patterns.},
   Journal = {Nature Communications},
   Volume = {9},
   Number = {1},
   Pages = {2715},
   Year = {2018},
   Month = {July},
   url = {http://dx.doi.org/10.1038/s41467-018-05121-8},
   Abstract = {How the brain preserves information about multiple
             simultaneous items is poorly understood. We report that
             single neurons can represent multiple stimuli by
             interleaving signals across time. We record single units in
             an auditory region, the inferior colliculus, while monkeys
             localize 1 or 2 simultaneous sounds. During dual-sound
             trials, we find that some neurons fluctuate between firing
             rates observed for each single sound, either on a
             whole-trial or on a sub-trial timescale. These fluctuations
             are correlated in pairs of neurons, can be predicted by the
             state of local field potentials prior to sound onset, and,
             in one monkey, can predict which sound will be reported
             first. We find corroborating evidence of fluctuating
             activity patterns in a separate dataset involving responses
             of inferotemporal cortex neurons to multiple visual stimuli.
             Alternation between activity patterns corresponding to each
             of multiple items may therefore be a general strategy to
             enhance the brain processing capacity, potentially linking
             such disparate phenomena as variable neural firing, neural
             oscillations, and limits in attentional/memory
             capacity.},
   Doi = {10.1038/s41467-018-05121-8},
   Key = {fds335640}
}

@article{fds324047,
   Author = {Caruso, VC and Pages, DS and Sommer, MA and Groh,
             JM},
   Title = {Similar prevalence and magnitude of auditory-evoked and
             visually-evoked activity in the frontal eye fields:
             Implications for multisensory motor control},
   Journal = {Journal of Neurophysiology},
   Volume = {in press},
   Number = {6},
   Pages = {3162-3173},
   Year = {2016},
   Month = {March},
   url = {http://dx.doi.org/10.1152/jn.00935.2015},
   Abstract = {Saccadic eye movements can be elicited by more than one type
             of sensory stimulus. This implies substantial
             transformations of signals originating in different sense
             organs as they reach a common motor output pathway. In this
             study, we compared the prevalence and magnitude of auditory-
             and visually-evoked activity in a structure implicated in
             oculomotor processing, the primate frontal eye fields (FEF).
             We recorded from 324 single neurons while 2 monkeys
             performed delayed saccades to visual or auditory targets. We
             found that 64% of FEF neurons were active upon presentation
             of auditory targets and 87% were active during
             auditory-guided saccades, compared to 75% and 84% for visual
             targets and saccades. As saccade onset approached, the
             average level of population activity in the FEF became
             indistinguishable on visual and auditory trials. FEF
             activity was better correlated with the movement vector than
             with the target location for both modalities In summary, the
             large proportion of auditory responsive neurons in the FEF,
             the similarity between visual and auditory activity levels
             at the time of the saccade and the strong correlation
             between the activity and the saccade vector suggest that
             auditory signals undergo tailoring to roughly match the
             strength of visual signals present in the FEF, facilitating
             accessing of a common motor output pathway.},
   Doi = {10.1152/jn.00935.2015},
   Key = {fds324047}
}