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| Publications [#140863] of John D Hamilton
Papers Published
- RJ Sherertz, JE Peacock, JW Sixbey, JD Folds, JH Bowdre, ES Huang, JD Hamilton, DL McDowell, Nonurban male homosexuals: epidemiologic, immunologic and virologic characteristics.,
The American journal of the medical sciences, UNITED STATES, vol. 288 no. 3
(October, 1984),
pp. 109-13, ISSN 0002-9629
(last updated on 2007/12/26)
Abstract:
Twenty asymptomatic male homosexuals living in North Carolina were evaluated looking at epidemiologic, immunologic and virologic characteristics. In ten subjects selected for inhalant nitrite use a significantly higher frequency of multiple drug abuse and a trend toward greater sexual promiscuity was found in comparison with ten nonnitrite users. None of the 20 subjects had chronic lymphadenopathy. Cytomegalovirus (CMV) was not found in urine, blood or throat washings, but was found in 29% of the subjects' semen specimens--a finding that was significantly linked (P less than .05) to the presence of CMV IgM antibody in serum. There were no abnormal helper lymphocytes: suppressor T lymphocyte ratios (all greater than 1.3) and lymphocyte mitogen stimulations were not different from heterosexual controls in contrast to frequent abnormalities reported in male homosexuals in metropolitan areas. If these immunologic findings are reproducible, they may be important in understanding why the Acquired Immunodeficiency Syndrome has clustered in large cities.
Keywords:
Adult • Cytomegalovirus Infections • Homosexuality* • Humans • Immunity* • Life Style* • Lymphocytes • Male • Nitrites • North Carolina • Sexual Behavior • Skin Tests • Substance-Related Disorders • Virus Diseases • epidemiology • epidemiology* • immunology
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