Publications [#278760] of Dennis A. Clements

Papers Published

1. Clements, DA; Booy, R; Dagan, R; Gilbert, GL; Moxon, ER; Slack, MP; Takala, A; Zimmermann, HP; Zuber, PL; Eskola, J, Comparison of the epidemiology and cost of Haemophilus influenzae type b disease in five western countries., Pediatric Infectious Disease Journal, vol. 12 no. 5 (May, 1993), pp. 362-367, ISSN 0891-3668 [8327294], [doi]
   (last updated on 2023/06/01)

   Abstract:
   To determine and compare the cost of Haemophilus influenzae type b (Hib) disease in Australia, Finland, Israel, Switzerland and the United Kingdom a collaborative study was undertaken. The incidence of Hib disease varies in these 5 countries from 34 to 58.5 cases per 100,000 children less than 5 years of age. Although the incidence of meningitis in this age group is similar (between 18 and 26/100,000) in these countries, the incidence of epiglottitis varies from 0 to 22.7/100,000. The cost of hospitalization and the frequency of sequelae are similar for 4 of the 5 countries; however, the break even cost of a vaccination program to prevent 90% of Hib disease is estimated to vary from $22 to $84 per child (US$). Because of a lower incidence of Hib disease and lower cost for hospitalization, these costs are considerably less than those for the United States ($301.64 using similar calculations).

   Keywords:
   Australia • Child, Preschool • Cohort Studies • Epiglottitis • Finland • Great Britain • Haemophilus Infections • Haemophilus influenzae* • Health Care Costs • Hospitalization • Humans • Immunization Schedule • Infant • Israel • Meningitis, Haemophilus • Switzerland • United States • complications • economics • economics* • epidemiology • epidemiology* • etiology • mortality