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Publications [#278772] of Dennis A. Clements

Papers Published

  1. Clements, DA, Modified varicella-like syndrome., Infectious Disease Clinics of North America, vol. 10 no. 3 (September, 1996), pp. 617-629, ISSN 0891-5520 [8856356], [doi]
    (last updated on 2023/06/01)

    Abstract:
    After incidental exposure to natural varicella, up to 18% of vaccinees reported a breakthrough infection known as modified varicella-like syndrome (MVLS) over up to 10 years of postvaccination follow-up, compared with natural varicella occurring in similarly aged unvaccinated children at the rate of 9% per year. Children with MVLS are frequently asymptomatic, and their disease is characterized by having fewer lesions, less fever, and lasting fewer days than natural varicella. When a case of MVLS occurs there are few secondary cases, suggesting that it is infrequently transmitted. Sequelae such as secondary bacterial infection, cerebellar ataxia, encephalitis, and pneumonia occur infrequently.

    Keywords:
    Chickenpox • Chickenpox Vaccine • Child • Costs and Cost Analysis • Herpes Zoster • Herpesvirus 3, Human • Humans • epidemiology • immunology • prevention & control • therapeutic use • virology*


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