Publications [#379978] of Tuan Vo-Dinh

Papers Published

1. Canning, AJ; Li, JQ; Atta, S; Wang, HN; Vo-Dinh, T, Nanoplasmonics biosensors: At the frontiers of biomedical diagnostics, TrAC - Trends in Analytical Chemistry, vol. 180 (November, 2024) [doi]
   (last updated on 2025/03/13)

   Abstract:
   This article presents an overview of various nanoplasmonics biosensors and their diverse applications, focusing on recent developments in our laboratory. We describe the versatility and effectiveness of different plasmonics-active platforms, ranging from solid substrates to adaptable nanoparticles like gold nanostars and nanorattles. The “Inverse Molecular Sentinel” (iMS) biosensing technology uses surface-enhanced Raman scattering (SERS) to detect nucleotide biomarkers associated with diseases ranging from acute infections to several types of cancer. We have also developed SERS-based nanochip systems capable of detecting DNA targets related to infectious disease biomarkers such as HIV, malaria, and dengue, promising advancements in global health diagnostics. Further, nanorattle-based biosensors are designed as “lab-in-a-stick” devices for rapid head and neck cancer diagnosis. Other technologies include plasmonics-enhanced lateral flow immunoassay systems, smartphone-based biosensing, and implantable biosensors or “smart tattoo” systems. These nanoplasmonics biosensors open new frontiers to rapid, simple, and effective detection systems for biomedical diagnostics.