Publications [#238221] of Henry G. Grabowski

Journal Articles

1. with Grabowski, HG; Wang, YR, The quantity and quality of worldwide new drug introductions, 1982-2003., Health affairs (Project Hope), vol. 25 no. 2 (March, 2006), pp. 452-460 [16522586], [doi]
   (last updated on 2026/01/17)

   Abstract:
   We examined trends in the introduction of new chemical entities (NCEs) worldwide from 1982 through 2003. Although annual introductions of NCEs decreased over time, introductions of high-quality NCEs (that is, global and first-in-class NCEs) increased moderately. Both biotech and orphan products enjoyed tremendous growth, especially for cancer treatment. Country-level analyses for 1993-2003 indicate that U.S. firms overtook their European counterparts in innovative performance or the introduction of first-in-class, biotech, and orphan products. The United States also became the leading market for first launch.