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Papers Published
- Purves, D; Voyvodic, JT; Magrassi, L; Yawo, H, Nerve terminal remodeling visualized in living mice by repeated examination of the same neuron.,
Science (New York, N.Y.), vol. 238 no. 4830
(November, 1987),
pp. 1122-1126 [3685967], [doi].
(last updated on 2023/06/01)
Abstract: The distribution of presynaptic endings on the surfaces of autonomic ganglion cells was mapped in living mice after intravenous administration of a styryl pyridinium dye. The staining and imaging techniques did not appear to damage the ganglion cells, or the synapses on them; these procedures could therefore be repeated after an arbitrary period. Observations of the same neurons at intervals of up to 3 weeks indicate that the pattern of preganglionic terminals on many of these nerve cells gradually changes.
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