Papers Published

1. Magrassi, L; Purves, D; Lichtman, JW, Fluorescent probes that stain living nerve terminals., The Journal of Neuroscience : the Official Journal of the Society for Neuroscience, vol. 7 no. 4 (April, 1987), pp. 1207-1214 [doi].
   (last updated on 2023/06/01)

   Abstract:
   We have evaluated the efficacy of 18 cationic mitochondrial dyes that, as a class, show some ability to stain living nerve terminals. Several of these agents provide excellent staining of neuromuscular junctions in a wide range of species. More detailed studies of the most effective of these dyes--4-(4-diethylaminostyryl)-N-methylpyridinium iodide (4-Di-2-ASP)--indicate that it has no lasting effect on the structure or function of motor nerve terminals. As demonstrated in the accompanying paper (Lichtman et al., 1987; see also Lichtman et al., 1986), 4-Di-2-ASP can therefore be used to follow the configuration of identified motor terminals over arbitrarily long intervals.