Slavic and Eurasian Studies Faculty Database
Slavic and Eurasian Studies
Arts & Sciences
Duke University

 HOME > Arts & Sciences > Slavics > Faculty    Search Help Login pdf version printable version 

Publications [#354957] of Edna Andrews

Papers Published

  1. Andrews, E; Eierud, C; Banks, D; Harshbarger, T; Michael, A; Rammell, C. "Effects of Lifelong Musicianship on White Matter Integrity and Cognitive Brain Reserve.." Brain Sciences 11.1 (January, 2021). [doi]
    (last updated on 2021/06/17)

    Abstract:
    There is a significant body of research that has identified specific, high-end cognitive demand activities and lifestyles that may play a role in building cognitive brain reserve, including volume changes in gray matter and white matter, increased structural connectivity, and enhanced categorical perception. While normal aging produces trends of decreasing white matter (WM) integrity, research on cognitive brain reserve suggests that complex sensory-motor activities across the life span may slow down or reverse these trends. Previous research has focused on structural and functional changes to the human brain caused by training and experience in both linguistic (especially bilingualism) and musical domains. The current research uses diffusion tensor imaging to examine the integrity of subcortical white matter fiber tracts in lifelong musicians. Our analysis, using Tortoise and ICBM-81, reveals higher fractional anisotropy, an indicator of greater WM integrity, in aging musicians in bilateral superior longitudinal fasciculi and bilateral uncinate fasciculi. Statistical methods used include Fisher's method and linear regression analysis. Another unique aspect of this study is the accompanying behavioral performance data for each participant. This is one of the first studies to look specifically at musicianship across the life span and its impact on bilateral WM integrity in aging.


Duke University * Arts & Sciences * Slavics * Faculty * Staff * Grad * Reload * Login